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| Registros recuperados : 15 | |
| 1. |  | CUNHA, C. O.; FRANCO, A. A. Efeito de altas temperaturas na nodulacao e crescimento de 10 leguminosas arboreas. In: REUNIAO BRASILEIRA DE FISIOLOGIA VEGETAL, 2, Piracicaba, 1989. Anais... Piracicaba, Sociedade Brasileira de Fisiologia Vegetal/ESALQ, 1989., v., p.249-, 1989.| Biblioteca(s): Embrapa Agrobiologia. |
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| 2. | | CUNHA, C. O.; OLIVEIRA, E.; FRANCO, A. A. Seleção de leguminosas arboreas e estirpes de rizobio para solos tropicais. In: , eds. In: SEMINARIO BIENAL DE PESQUISA DA UFRRJ, 4, MOSTRA COMUNITARIA DE PESQUISA, ENSINO E PRODUCAO, 1, Rio de Janeiro, 1988. Resumos... Rio de Janeiro, UFRRJ, Departamento de Pesquisa e Pos-Graduacao. p.163.. , 1988.| Biblioteca(s): Embrapa Agrobiologia. |
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| 5. | | FRANCO, A. A.; CAMPELLO, E. F. C.; MONTEIRO, E. M. S.; CUNHA, C. O.; CAMPOS NETO, D.; DOBEREINER, J. Nodulated legume trees for the recuperation of acid tropical soils. In: Conference of the North American Symbiotic Nitrogen Fixation, 12, Iowa. Proceedings... Iowa : Iowa State University., v., p.70-, 1989.| Biblioteca(s): Embrapa Agrobiologia. |
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| 6. | | MACORINI, L. F.; CUNHA, C. O.; SÁ, R. A.; MELO, A. M. M. F.; MERCANTE, F. M. Atividade antifúngica de Burkholderia spp. isoladas de nódulos: Candida albicans In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 25., 2009, Porto de Galinhas, PE. Anais... [São Paulo]: Sociedade Brasileira de Microbiologia, 2009 1 CD-ROM. Resumo - ID:2056-2| Biblioteca(s): Embrapa Agropecuária Oeste. |
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| 7. | | FRANCO, A. A.; CAMPELLO, E. F. C.; CAMPOS NETO, D.; CUNHA, C. O.; MONTEIRO, E. M. S. Uso de leguminosas arboreas, rizobio e micorriza na recuperacao de latossolo decapitado. In: FEIRA E CONGRESSO NACIONAL DE BIOTECNOLOGIA, 2, Sao Paulo. Resumos... Sao Paulo : Associacao Brasileira de Empresas de Biotecnologia.,, 1991. p. 25| Biblioteca(s): Embrapa Agrobiologia. |
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| 8. | | NASCIMENTO FILHO, A. A. do; MELO, C. M. L. de; CUNHA, C. O.; GOULART, A. C. P.; STRALIOTTO, R.; MERCANTE, F. M.; CAVADA, B. S. Atividade antifúngica de Burkholderia spp. isoladas de nódulos: fungos fitopatogênicos. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 25., 2009, Porto de Galinhas, PE. Anais... [São Paulo]: Sociedade Brasileira de Microbiologia, 2009 ResumoID:2056-1| Biblioteca(s): Embrapa Agropecuária Oeste. |
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| 9. | | do NASCIMENTO FILHO, A. A.; DE MELO, C. M. L.; CUNHA, C. O.; GOULART, A. C. P.; STRALIOTTO, R.; MERCANTE, F. M.; CAVADA, B. S. Atividade antifúngica de Burkholderia spp. Isoladas de nódulos: fungos fitopatogênicos In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 25.,2009, Porto de Galinhas, PE. Anais... [São Paulo]: Sociedade Bras. de Microbiologia, 2009. 01 01 de 01| Biblioteca(s): Embrapa Agrobiologia. |
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| 10. | | FRANCO, A. A.; CAMPOS NETO, D.; CUNHA, C. O.; CAMPELLO, E. F.; MONTEIRO, E. M. S.; SANTOS, C. J. F.; FARIA, S. M. DE. Revegetacao de solos degradados. In: Workshop sobre Recuperacao de Areas Degradadas, 1, Itaguai, 1991. Anais... Itaguai : Universidade Federal Rural do Rio de Janeiro, Instituto de Florestas, 1990. p.133-157., v., p.-, 1991.| Biblioteca(s): Embrapa Agrobiologia. |
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| 11. | | FRANCO, A. A.; CAMPOS NETO, D.; CUNHA, C. O.; CAMPELLO, E. F.; MONTEIRO, E. M. S.; SANTOS, C. J. F.; FONTES, A. M.; FARIA, S. M. de. Revegetacao de solos degradados. In: WORKSHOP SOBRE RECUPERACAO DE AREAS DEGRADADAS, 1., 1990, Itaguai. Anais... Itaguai: Universidade Federal Rural do Rio de Janeiro, 1991. p.133-145.| Biblioteca(s): Embrapa Florestas; Embrapa Solos. |
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| 12. | | VASCONCELOS, M. A. de; CUNHA, C. O.; ARRUDA, F. V. S.; CARNEIRO, V. A.; MERCANTE, F. M.; NASCIMENTO NETO, L. G. do; SOUSA, G. S. de; ROCHA, B. A. M.; TEIXEIRA, E. H.; CAVADA, B. S.; SANTOS, R. P. dos. Lectin from Canavalia brasiliensis seeds (ConBr) is a valuable biotechnological tool to stimulate the growth of Rhizobium tropici in vitro. Molecules, v. 17, n. 5, p. 5244-5254, May 2012.| Biblioteca(s): Embrapa Agropecuária Oeste. |
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| 13. | | VASCONCELOS, M. A. de; CUNHA, C. O.; ARRUDA, F. V. S.; CARNEIRO, V. A.; BASTOS, R. M.; MERCANTE, F. M.; NASCIMENTO, K. S. do; CAVADA, B. S.; SANTOS, R. P. dos; TEIXEIRA, E. H. Effect of leguminous lectins on the growth of Rhizobium tropici CIAT899. Molecules, v. 18, n. 5, p. 5792-5803, May 2013.| Biblioteca(s): Embrapa Agropecuária Oeste. |
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| 14. | | CUNHA, C. O.; NASCIMENTO FILHO, A. A. do; MELO, C. M. L. de; MERCANTE, F. M.; FARIA, S. M. de; STRALIOTTO, R.; PORTO, A. L. F.; CAVADA, B. S. Nódulos de leguminosas são fonte de Burkholderia spp. não-patogênicas com grande diversidade e potencial biotecnológico. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 25., 2009, Porto de Galinhas, PE. Anais... [São Paulo]: Sociedade Brasileira de Microbiologia, 2009 1 CD-ROM. Resumo - ID:1856-2| Biblioteca(s): Embrapa Agropecuária Oeste. |
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| 15. | | CUNHA, C. O.; do NASCIMENTO FILHO, A. A.; DE MELO, C. M. L.; MERCANTE, F. M.; FARIA, S. M. de; STRALIOTTO, R.; PORTO, A. L. F.; CAVADA, B. S. Nódulos de leguminosas são fonte de Burkholderia spp. não-patogênicas com grande diversidade e potencial biotecnológico. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 25.,2009, Porto de Galinhas, PE. Anais... [São Paulo]: Sociedade Bras. de Microbiologia, 2009. 01 p.01 de 01| Biblioteca(s): Embrapa Agrobiologia. |
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| Registros recuperados : 15 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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Data corrente: |
08/09/2020 |
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Data da última atualização: |
10/09/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. |
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Afiliação: |
JULIANA AFONSO, UFSCar; MARINA RUFINO SALINAS FORTES, The University of Queensland; ANTONIO REVERTER, Agriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Brisbane; WELLISON JARLES DA SILVA DINIZ, UFSCar; ALINE SILVA MELLO CESAR, Esalq/USP; ANDRESSA OLIVEIRA DE LIMA, UFSCar; JULIANA PETRINI, UNIFAL; MARCELA M. DE SOUZA, Iowa State University; LUIZ LEHMANN COUTINHO, Esalq/USP; GERSON BARRETO MOURÃO, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; CAIO FERNANDO GROMBONI, Bahia Federal Institute of Education, Science and Technology, Ilhéus; ANA RITA ARAÚJO NOGUEIRA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Scientific Reports, v. 10, n. 1, p. 1-16, 2020 |
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DOI: |
https://doi.org/10.1038/s41598-020-65454-7 |
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Idioma: |
Inglês |
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Notas: |
Article: 8436. |
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Conteúdo: |
Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. MenosMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators describe... Mostrar Tudo |
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Palavras-Chave: |
Expressão gênica. |
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Thesagro: |
Bos Indicus; Gado Nelore. |
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Thesaurus NAL: |
Cattle; Gene expression. |
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Categoria do assunto: |
--
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/215819/1/AP-Genetic-regulators-2020.pdf
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Marc: |
LEADER 02716naa a2200361 a 4500
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024 7 $ahttps://doi.org/10.1038/s41598-020-65454-7$2DOI
100 1 $aAFONSO, J.
245 $aGenetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach.$h[electronic resource]
260 $c2020
500 $aArticle: 8436.
520 $aMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals.
650 $aCattle
650 $aGene expression
650 $aBos Indicus
650 $aGado Nelore
653 $aExpressão gênica
700 1 $aFORTES, M. R. S.
700 1 $aREVERTER, A.
700 1 $aDINIZ, W. J. da S.
700 1 $aCESAR, A. S. M.
700 1 $aLIMA, A. O. de
700 1 $aPETRINI, J.
700 1 $aSOUZA, M. de S.
700 1 $aCOUTINHO, L. L.
700 1 $aMOURÃO, G. B.
700 1 $aZERLOTINI NETO, A.
700 1 $aGROMBONI, C. F.
700 1 $aNOGUEIRA, A. R. A.
700 1 $aREGITANO, L. C. de A.
773 $tScientific Reports$gv. 10, n. 1, p. 1-16, 2020
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