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 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
27/05/1994 |
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Data da última atualização: |
28/12/2016 |
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Autoria: |
CASTRO, V. L. S. S. de; PALERMO-NETO, J. |
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Afiliação: |
VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; J. PALERMO-NETO, USP. |
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Título: |
Effects of long-term aldrin administration on seizure susceptibility of rats. |
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Ano de publicação: |
1989 |
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Fonte/Imprenta: |
Pharmacology & Toxicology, v.65, p.204-208, 1989. |
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Idioma: |
Inglês |
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Conteúdo: |
The effects of long-term administration of sub-convulsive doses of aldrin, an organochlorinated pesticide, on seizure susceptibility of rats were studied. Results show that treatment with the pesticide made the rats more susceptible to sound-induced seizure; an increment in post-seizure depression time after maximal electroschock administration was also observed in aldrin-treated animals. Aldrin administration displaced the control dose-response curves constructed for amphetamine and pentylenetetrazol to the left and right, respectively; no differences were detected between control and aldrin-treated rats for strychnine, picrotoxin or 3-mercaptopropionic acid. The results, discussed in the light of the effects of aldrin on biogenic amines or on the electrophysiology of neurones suggested an involvement of both noradrenergic and alteration excitability of the CNS with the observed increments on seizure susceptibility. |
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Palavras-Chave: |
Insecticide; Organochloride; Pesticide; Rat. |
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Thesagro: |
Aldrin. |
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Thesaurus Nal: |
toxicology. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01500naa a2200205 a 4500
001 1011947
005 2016-12-28
008 1989 bl uuuu u00u1 u #d
100 1 $aCASTRO, V. L. S. S. de
245 $aEffects of long-term aldrin administration on seizure susceptibility of rats.$h[electronic resource]
260 $c1989
520 $aThe effects of long-term administration of sub-convulsive doses of aldrin, an organochlorinated pesticide, on seizure susceptibility of rats were studied. Results show that treatment with the pesticide made the rats more susceptible to sound-induced seizure; an increment in post-seizure depression time after maximal electroschock administration was also observed in aldrin-treated animals. Aldrin administration displaced the control dose-response curves constructed for amphetamine and pentylenetetrazol to the left and right, respectively; no differences were detected between control and aldrin-treated rats for strychnine, picrotoxin or 3-mercaptopropionic acid. The results, discussed in the light of the effects of aldrin on biogenic amines or on the electrophysiology of neurones suggested an involvement of both noradrenergic and alteration excitability of the CNS with the observed increments on seizure susceptibility.
650 $atoxicology
650 $aAldrin
653 $aInsecticide
653 $aOrganochloride
653 $aPesticide
653 $aRat
700 1 $aPALERMO-NETO, J.
773 $tPharmacology & Toxicology$gv.65, p.204-208, 1989.
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Embrapa Meio Ambiente (CNPMA) |
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| Registros recuperados : 4 | |
| 1. |  | SILVA, L. O. C. da; TSURUTA, S.; BERTRAND, J. K.; GONDO, A.; JOSAHKIAN, L. A. Performance group in G X E study for genetic evaluation of growth in Brazillian Nellore. In: ADSA-PSA-AMPA-ASAS JOINT ANNUAL MEETING, 2009, Montreal. Abstracts. Montreal: ADSA: ASAS, 2009. Disponível em:< http://adsa.asas.org/meetings/2009/abstracts/toc.htm > Acesso em: 15 dez. 2009. Publicado em: Journal of Animal Science, Champaign, v. 87, E-Supplement 2/J; Journal of Dairy Science, Champaign, v. 92, E-Supplement 1. p. 18. Breeding and Genetics : Poultry Breeding, and Genetics of Disease. 1 p. Trabalho M.48.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Corte. |
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| 2. | | SILVA, L. O. C.; TSURUTA, S.; BERTRAND, J. K.; GONDO, A.; NOBRE, P. R. C.; TORRES JÚNIOR, R. A. A.; MACHADO, C. H. C. An approach for considering genotype x environment interaction in the genetic evaluations of Zebu beef cattle in Brazil. In: ADSA-PSA-AMPA-ASAS JOINT ANNUAL MEETING, 2008, Indianapolis. Abstracts. Indianapolis: ADSA: ASAS, 2008. Disponível em:< http://adsa.asas.org/meetings/2008/abstracts/TOC.htm > Acesso em: 26 mar. 2009. Publicado em: Journal of Animal Science, Champaign, v. 86, E-Supplement 2; Journal of Dairy Science, Champaign, v. 91, E-Supplement 1. p. 207 1 CD-ROM. Breeding and Genetics II. O202. Trabalho W46.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Corte. |
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| 3. | | SILVA, L. O. C. da; TSURUTA, S.; TORRES JUNIOR, R. A. de A.; BERTRAND, J. K.; GONDO, A.; NOBRE, P. R. C.; JOSAHKIAN, L. A. Alternativas para manejar dados relacionados à idade ao primeiro parto em Nelore, quando se pretende estimar parâmetros genéticos. In: REUNIÓN BIENAL [DE LA] ASOCIACIÓN LATINOAMERICANA DE PRODUCCIÓN ANIMAL, 21., 2009, San Juan. Producción animal em tiempos de crisis: memórias... San Juan: ALPA, 2009. p. 106-110 (GFR-19C).| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Gado de Corte. |
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| 4. | | SILVA, L. O. C. da; TSURUTA, S.; BERTRAND, J. K.; TORRES JUNIOR, R. A. de A.; GONDO, A.; NOBRE, P. R. C.; NIETO, L. M.; JOSAHKIAN, L. A.; ROSA, A. do N. Including data on culled heifers on breeding values for age at first calving, Nellore cattle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 9., 2010, Leipzig. Proceedings... Leipzig: German Society fo Animal Science, 2010. 4 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Corte. |
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| Registros recuperados : 4 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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