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| Registros recuperados : 16 | |
| 2. |  | COSTA, C. T. C.; OLIVEIRA, L. M. B.; CAMURÇA-VASCONCELOS, A. L. F.; VIEIRA, L. da S.; BEVILÁQUA, C. M. L. Atividade anti-helmíntica de Cocos nucifera L. In: CONGRESSO BRASILEIRO DE PARASITOLOGIA VETERINÁRIA, 15.; SEMINÁRIO DE PARASITOLOGIA VETERINÁRIA DOS PAÍSES DO MERCOSUL, 2., 2008, Curitiba. Programa e resumos. Curitiba: UFPR: Universidade Estadual de Londrina, 2008. p. 36-41.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 4. | | OLIVEIRA, L. M. B. de; BEVILAQUA, C. M. L.; MORAIS, S. M. de; CAMURÇA-VASCONCELOS, A. L. F.; MACEDO, I. T. F. Plantas taniníferas e o controle de nematóides gastrintestinais de pequenos ruminantes. Ciência Rural, Santa Maria, v. 41, n. 11, p. 1967-1974, nov. 2011.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 5. | | CAMURÇA-VASCONCELOS, A. L. F.; BEVILAQUA, C. M. L.; MORAIS, S. M.; MACIEL, M. V.; COSTA, C. T. C.; MACEDO, I. T. F.; OLIVEIRA, L. M. B.; BRAGA, R. R.; SILVA, R. A.; VIEIRA, L. da S. Anthelmintic activity of Croton zehntneri and Lippia sidoides essential oils. Veterinary Parasitology, v. 148, n. 3/4, p. 288-294, Nov. 2007.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 6. | | MACEDO, I. T. F.; BEVILAQUA, C. M. L.; OLIVEIRA, L. M. B. de; CAMURÇA-VASCONCELOS, A. L. F.; VIEIRA, L. da S.; OLIVEIRA, F. R.; QUEIRÓZ JÚNIOR, E. M.; TOMÉ, A. R. da; NASCIMENTO, N. R. F. Anthelmintic effect of Eucalyptus staigeriana essential oil against goat gastrointestinal nematodes. Veterinary Parasitology, v. 173, n. 1/2, p. 93-98, Oct., 2010.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 7. | | COSTA, C. T. C.; CAMURÇA-VASCONCELOS, A. L. F.; MACIEL, M. V.; MORAIS, S. M.; CASTRO, C. M. S.; VALENTE, M. N.; GOMES, F. F.; BEVILAQUA, C. M. L. Atividade anti-helmíntica de Zadirachta indica sobre nematódeos gastrintestinais de pequenos ruminantes. Revista Brasileira de Parasitologia Veterinária, v. 13, p. 264, 2004. Suplemento 1. Resumo 226. Edição de anais do 13o. Congresso Brasileiro de Parasitologia Veterinária e o 1o. Simpósio Latino-Americano de Rickettsioses, Ouro Preto, MG, set. 2004.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 8. | | MACEDO, I. T. F.; BEVILAQUA, C. M. L.; OLIVEIRA, L. M. B. de; CAMURÇA-VASCONCELOS, A. L. F.; VIEIRA, L. da S.; OLIVEIRA, F. R.; QUEIROZ JÚNIOR, E. M.; PORTELA, B. G.; BARROS, R. S.; CHAGAS, A. C. de S. Atividade ovicida e larvicida in vitro do óleo essencial de Eucalyptus globulus sobre Haemonchus contortus. Revista Brasileira de Parasitologia Veterinária, v. 18, n. 3, p. 62-66, jul./set. 2009. Título em inglês: Ovicidal and larvicidal activity in vitro of Eucalyptus globulus essential oils on Haemonchus contortus.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 9. | | SANTOS, J. M. L. dos; MONTEIRO, J. P.; RIBEIRO, W. L. C.; MACEDO, I. T. F.; CAMURÇA-VASCONCELOS, A. L. F.; VIEIRA, L. da S.; BEVILÁQUA, C. M. L. Identification and quantification of benzimidazole resistance polymorphisms in Haemonchus contortus isolated in Northeastern Brazil. Veterinary Parasitology, v. 199, n. 3/4, p. 160-164, Jan. 2014.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 10. | | OLIVEIRA, L. M. B.; MACEDO, I. T. F.; VIEIRA, L. da S.; CAMURÇA-VASCONCELOS, A. L. F.; TOMÉ, A. R.; SAMPAIO, R. A.; LOUVANDINI, H.; BEVILAQUA, C. M. L. Effects of Mimosa tenuiflora on larval establishment of Haemonchus contortus in sheep. Veterinary Parasitology, v. 196, n. 3/4, p. 341-346, Sept. 2013.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 11. | | COSTA, C. T. C.; BEVILAQUA, C. M. L.; MORAIS, S. M. de; OLIVEIRA, L. M. B. de; CAMURÇA-VASCONCELOS, A. L. F.; MACIEL, M. do V.; LIMA, K. S. B. de. Ovicidal and larvicidal activity of Cocos nucifera L. extracts on Haemonchus contortus. Ciência Animal, Fortaleza, v. 21, n. 2, p. 87-95, 2011.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 12. | | RIBEIRO, W. L. C.; CAMURÇA-VASCONCELOS, A. L. F.; SANTOS, J. M. L. dos; MACEDO, I. T. F.; RIBEIRO, J. de C.; OLIVEIRA, E. F. de; PAULA, H. C. B. de; BEVILAQUA, C. J. L. The use of Eucalyptus staigeriana nanoemulsion for control of sheep haemonchosis. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 3, p. 221-226, março 2017. Título em português: Uso da nanoemulsão de Eucalyptus staigeriana no controle da hemoncose em ovinos.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 13. | | OLIVEIRA, L. M. B. de; BEVILAQUA, C. M. L.; COSTA, C. T. C.; MACEDO, I. T. F.; BARROS, R. S.; RODRIGUES, A. C. M.; CAMURÇA-VASCONCELOS, A. L. F.; MORAIS, S. M.; LIMA, Y. C.; VIEIRA, L. da S.; NAVARRO, A. M. C. Anthelmintic activity of Cocos nucifera L. against sheep gastrointestinal nematodes. Veterinary Parasitology, v. 159, n. 1, p. 55-59, 2009.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 14. | | CAMURÇA-VASCONCELOS, A. L. F.; BEVILAQUA, C. M. L.; MORAIS, S. M.; MACIEL, M. V.; COSTA, C. T. C.; MACEDO, I. T. F.; OLIVEIRA, L. M. B.; BRAGA, R. R.; SILVA, R. A.; VIEIRA, L. da S.; NAVARRO, A. M. C. Anthelmintic activity of Lippia sidoides essential oil on sheep gastrointestinal nematodes. Veterinary Parasitology, v. 154, n. 1/2, p. 167-170, Jun. 2008.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 15. | | SANTOS, J. M. L. dos; MONTEIRO, J. P.; RIBEIRO, W. L. C.; MACEDO, I. T. F.; FONTENELE, J. A.; FREITAS, E.; RIBEIRO, J. de C.; SAMPAIO, R. A.; ARAÚJO FILHO, V.; CAMURÇA-VASCONCELOS, A. L. F.; VIEIRA, L. da S.; BEVILÁQUA, C. M. L. Identification and quantification of polymorphisms responsible for the resistance to benzimidazoles in Haemonchus contortus isolated in the State of Ceara, Northeastern of Brazil. In: INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 24., 2013, Perth. [Electonic abstracts]... Perth: WAAVP, 2013. Poster 125. p. 518.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 16. | | MACEDO, I. T. F.; BEVILAQUA, C. M. L.; OLIVEIRA, L. M. B. de; CAMURÇA-VASCONCELOS, A. L. F.; AMÓRA, S. S. A.; PORTELA, B. G.; QUEIRÓZ JÚNIOR, E. M. de; BARROS, R. S.; MESQUITA, M. de A.; VIEIRA, L. da S.; MACIEL, M. V. Investigation of anthelmintic activity of Eucalyptus staigeriana essential oil on goat gastrointestinal nematodes. In: WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 22., 2009, Calgary. Proceedings... Calgary: WAAVP, 2009. 1 CD-ROM. Ref. P01.56| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| Registros recuperados : 16 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
18/12/2018 |
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Data da última atualização: |
24/01/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; VERARDO, L. L.; AZEVEDO, A. L. S.; VANDENPLAS, J.; SOARES, A. C. C.; SEVILLANO, C. A.; VERONEZE R; PIRES, M. de F. A.; FREITAS, C. de; PRATA, M. C. de A.; FURLONG, J.; VERNEQUE, R. da S.; MARTINS, M. F.; PANETTO, J. C. do C.; CARVALHO, W. A.; GOBO, D. O. R.; SILVA, M. V. G. B.; MACHADO, M. A. |
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Afiliação: |
PAMELA I. OTTO, UFV; SIMONE ELIZA FACIONI GUIMARAES, UFV; LUCAS L. VERARDO, UFV; ANA LUISA SOUSA AZEVEDO, CNPGL; J. VANDENPLAS, Wageningen University; ALINE C. C. SOARES, UFV; CLAUDIA A. SEVILLANO, Wageningen University; Topigs Norsvin Research Center, Beuningen; RENATA VERONEZE, UFV; MARIA DE FATIMA AVILA PIRES, CNPGL; CELIO DE FREITAS, CNPGL; MARCIA CRISTINA DE AZEVEDO PRATA, CNPGL; JOHN FURLONG, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; MARTA FONSECA MARTINS, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; WANESSA ARAUJO CARVALHO, CNPGL; DIEGO O. R. GOBO, UFV; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARCO ANTONIO MACHADO, CNPGL. |
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Título: |
Genome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle: A deeper look into this intricate mechanism. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Journal of Dairy Science, v. 101, n. 12, p. 11020-11032, 2018. |
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DOI: |
10.3168/jds.2017-14223 |
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Idioma: |
Inglês |
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Conteúdo: |
ABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle. MenosABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network a... Mostrar Tudo |
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Palavras-Chave: |
Breed of origin; Gene network; Gir × Holstein crossbred. |
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Thesaurus NAL: |
Genetic variance. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03793naa a2200397 a 4500
001 2101869
005 2023-01-24
008 2018 bl uuuu u00u1 u #d
024 7 $a10.3168/jds.2017-14223$2DOI
100 1 $aOTTO, P. I.
245 $aGenome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle$bA deeper look into this intricate mechanism.$h[electronic resource]
260 $c2018
520 $aABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle.
650 $aGenetic variance
653 $aBreed of origin
653 $aGene network
653 $aGir × Holstein crossbred
700 1 $aGUIMARÃES, S. E. F.
700 1 $aVERARDO, L. L.
700 1 $aAZEVEDO, A. L. S.
700 1 $aVANDENPLAS, J.
700 1 $aSOARES, A. C. C.
700 1 $aSEVILLANO, C. A.
700 1 $aVERONEZE R
700 1 $aPIRES, M. de F. A.
700 1 $aFREITAS, C. de
700 1 $aPRATA, M. C. de A.
700 1 $aFURLONG, J.
700 1 $aVERNEQUE, R. da S.
700 1 $aMARTINS, M. F.
700 1 $aPANETTO, J. C. do C.
700 1 $aCARVALHO, W. A.
700 1 $aGOBO, D. O. R.
700 1 $aSILVA, M. V. G. B.
700 1 $aMACHADO, M. A.
773 $tJournal of Dairy Science$gv. 101, n. 12, p. 11020-11032, 2018.
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