| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Pecuária Sudeste; Embrapa Suínos e Aves. |
|
Data corrente: |
09/05/2024 |
|
Data da última atualização: |
27/05/2024 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
DAL PIZZOL, M. S.; IBELLI, A. M. G.; CANTAO, M. E.; CAMPOS, F. G.; OLIVEIRA, H. C. de; PEIXOTO, J. de O.; FERNANDES, L. T.; TAVERNARI, F. de C.; MORES, M. A. Z.; BASTOS, A. P. A.; LEDUR, M. C. |
|
Afiliação: |
MARIANE SPUDEIT DAL PIZZOL, UNIVERSIDADE DO ESTADO DE SANTA CATARINA; ADRIANA MERCIA GUARATINI IBELLI, CPPSE; MAURICIO EGIDIO CANTAO, CNPSA; FRANCELLY GERALDA CAMPOS, UNIVERSIDADE FEDERAL DE VIÇOSA; HANIEL CEDRAZ DE OLIVEIRA, UNIVERSIDADE FEDERAL DE VIÇOSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; LANA TEIXEIRA FERNANDES; FERNANDO DE CASTRO TAVERNARI, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; ANA PAULA ALMEIDA BASTOS, CNPSA; MONICA CORREA LEDUR, CNPSA. |
|
Título: |
Differential expression of miRNAs associated with pectoral myopathies in young broilers: insights from a comparative transcriptome analysis. |
|
Ano de publicação: |
2024 |
|
Fonte/Imprenta: |
BMC Genomics, v. 25, n. 104, p. 1-14, 2024. |
|
DOI: |
https://doi.org/10.1186/s12864-024-09983-9 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: Introduction: White Striping (WS) and Wooden Breast (WB) pectoral myopathies are relevant disorders for con- temporary broiler production worldwide. Several studies aimed to elucidate the genetic components associated with the occurrence of these myopathies. However, epigenetic factors that trigger or differentiate these two condi- tions are still unclear. The aim of this study was to identify miRNAs differentially expressed (DE) between normal and WS and WB-affected broilers, and to verify the possible role of these miRNAs in metabolic pathways related to the manifestation of these pectoral myopathies in 28-day-old broilers. Results: Five miRNAs were DE in the WS vs control (gga-miR-375, gga-miR-200b-3p, gga-miR-429-3p, gga-miR- 1769-5p, gga-miR-200a-3p), 82 between WB vs control and 62 between WB vs WS. Several known miRNAs were associated with WB, such as gga-miR-155, gga-miR-146b, gga-miR-222, gga-miR-146-5p, gga-miR- 29, gga-miR-21-5p, gga-miR-133a-3p and gga-miR-133b. Most of them had not previously been associated with the development of this myopathy in broilers. We also have predicted 17 new miRNAs expressed in the broilers pectoral muscle. DE miRNA target gene ontology analysis enriched 6 common pathways for WS and WB compared to control: autophagy, insulin signaling, FoxO signaling, endocytosis, and metabolic pathways. The WS vs control contrast had two unique path- ways, ERBB signaling and the mTOR signaling, while WB vs control had 14 unique pathways, with ubiquitin-mediated proteolysis and endoplasmic reticulum protein processing being the most significant. Conclusions: We found miRNAs DE between normal broilers and those affected with breast myopathies at 28 days of age. Our results also provide novel evidence of the miRNAs role on the regulation of WS and in the differentiation of both WS and WB myopathies. Overall, our study provides insights into miRNA-mediated and pathways involved in the occurrence of WS and WB helping to better understand these chicken growth disorders in an early age. These findings can help developing new approaches to reduce these complex issues in poultry production pos- sibly by adjustments in nutrition and management conditions. Moreover, the miRNAs and target genes associated with the initial stages of WS and WB development could be potential biomarkers to be used in selection to reduce the occurrence of these myopathies in broiler production. MenosAbstract: Introduction: White Striping (WS) and Wooden Breast (WB) pectoral myopathies are relevant disorders for con- temporary broiler production worldwide. Several studies aimed to elucidate the genetic components associated with the occurrence of these myopathies. However, epigenetic factors that trigger or differentiate these two condi- tions are still unclear. The aim of this study was to identify miRNAs differentially expressed (DE) between normal and WS and WB-affected broilers, and to verify the possible role of these miRNAs in metabolic pathways related to the manifestation of these pectoral myopathies in 28-day-old broilers. Results: Five miRNAs were DE in the WS vs control (gga-miR-375, gga-miR-200b-3p, gga-miR-429-3p, gga-miR- 1769-5p, gga-miR-200a-3p), 82 between WB vs control and 62 between WB vs WS. Several known miRNAs were associated with WB, such as gga-miR-155, gga-miR-146b, gga-miR-222, gga-miR-146-5p, gga-miR- 29, gga-miR-21-5p, gga-miR-133a-3p and gga-miR-133b. Most of them had not previously been associated with the development of this myopathy in broilers. We also have predicted 17 new miRNAs expressed in the broilers pectoral muscle. DE miRNA target gene ontology analysis enriched 6 common pathways for WS and WB compared to control: autophagy, insulin signaling, FoxO signaling, endocytosis, and metabolic pathways. The WS vs control contrast had two unique path- ways, ERBB signaling and the mTOR signaling, while WB vs control had 14 unique pathways, ... Mostrar Tudo |
|
Palavras-Chave: |
Epigenética; Peito; RNAs pequenos; Small RNAs; White striping; Wooden breast. |
|
Thesagro: |
Galinha; RNA. |
|
Thesaurus Nal: |
Chickens; Epigenetics. |
|
Categoria do assunto: |
--
G Melhoramento Genético |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1164173/1/DifferentialExpressionMiRNAS.pdf
|
|
Marc: |
LEADER 03529naa a2200373 a 4500
001 2164173
005 2024-05-27
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1186/s12864-024-09983-9$2DOI
100 1 $aDAL PIZZOL, M. S.
245 $aDifferential expression of miRNAs associated with pectoral myopathies in young broilers$binsights from a comparative transcriptome analysis.$h[electronic resource]
260 $c2024
520 $aAbstract: Introduction: White Striping (WS) and Wooden Breast (WB) pectoral myopathies are relevant disorders for con- temporary broiler production worldwide. Several studies aimed to elucidate the genetic components associated with the occurrence of these myopathies. However, epigenetic factors that trigger or differentiate these two condi- tions are still unclear. The aim of this study was to identify miRNAs differentially expressed (DE) between normal and WS and WB-affected broilers, and to verify the possible role of these miRNAs in metabolic pathways related to the manifestation of these pectoral myopathies in 28-day-old broilers. Results: Five miRNAs were DE in the WS vs control (gga-miR-375, gga-miR-200b-3p, gga-miR-429-3p, gga-miR- 1769-5p, gga-miR-200a-3p), 82 between WB vs control and 62 between WB vs WS. Several known miRNAs were associated with WB, such as gga-miR-155, gga-miR-146b, gga-miR-222, gga-miR-146-5p, gga-miR- 29, gga-miR-21-5p, gga-miR-133a-3p and gga-miR-133b. Most of them had not previously been associated with the development of this myopathy in broilers. We also have predicted 17 new miRNAs expressed in the broilers pectoral muscle. DE miRNA target gene ontology analysis enriched 6 common pathways for WS and WB compared to control: autophagy, insulin signaling, FoxO signaling, endocytosis, and metabolic pathways. The WS vs control contrast had two unique path- ways, ERBB signaling and the mTOR signaling, while WB vs control had 14 unique pathways, with ubiquitin-mediated proteolysis and endoplasmic reticulum protein processing being the most significant. Conclusions: We found miRNAs DE between normal broilers and those affected with breast myopathies at 28 days of age. Our results also provide novel evidence of the miRNAs role on the regulation of WS and in the differentiation of both WS and WB myopathies. Overall, our study provides insights into miRNA-mediated and pathways involved in the occurrence of WS and WB helping to better understand these chicken growth disorders in an early age. These findings can help developing new approaches to reduce these complex issues in poultry production pos- sibly by adjustments in nutrition and management conditions. Moreover, the miRNAs and target genes associated with the initial stages of WS and WB development could be potential biomarkers to be used in selection to reduce the occurrence of these myopathies in broiler production.
650 $aChickens
650 $aEpigenetics
650 $aGalinha
650 $aRNA
653 $aEpigenética
653 $aPeito
653 $aRNAs pequenos
653 $aSmall RNAs
653 $aWhite striping
653 $aWooden breast
700 1 $aIBELLI, A. M. G.
700 1 $aCANTAO, M. E.
700 1 $aCAMPOS, F. G.
700 1 $aOLIVEIRA, H. C. de
700 1 $aPEIXOTO, J. de O.
700 1 $aFERNANDES, L. T.
700 1 $aTAVERNARI, F. de C.
700 1 $aMORES, M. A. Z.
700 1 $aBASTOS, A. P. A.
700 1 $aLEDUR, M. C.
773 $tBMC Genomics$gv. 25, n. 104, p. 1-14, 2024.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Algodão. |
|
Data corrente: |
09/03/2023 |
|
Data da última atualização: |
12/03/2023 |
|
Tipo da produção científica: |
Artigo em Anais de Congresso |
|
Autoria: |
ALMEIDA, C. A. de; REINALDO, L. R. L. R.; ARRUDA, L. V. de; FERREIRA, D. R. F.; SANTOS, J. W. dos. |
|
Afiliação: |
CLEANDRO ALVES DE ALMEIDA, UEPB; LIDIAM RODRIGUES LOPES RAMOS REINALDO, UEPB; LUCIENE VIEIRA DE ARRUDA, UEPB; DÉBORA VANESSA REGIS FERREIRA, UEPB; JOSÉ WELLINGTON DOS SANTOS, CNPA. |
|
Título: |
Análise de argissolo para fins de fertilidade em função de critérios de amostragem e do instrumento de coleta das amostras no município de Guarabira - PB. |
|
Ano de publicação: |
2011 |
|
Fonte/Imprenta: |
In: CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 33., 2011, Uberlândia. Solo nos biomas brasileiros: sustentabilidade e mudanças climáticas: anais. [Uberlândia]: SBCS: UFU: ICIAG, 2011. 1 CD-ROM. |
|
Páginas: |
4 p. |
|
Idioma: |
Português |
|
Conteúdo: |
A utilização da análise química na prática do manejo agrícola é imprescindível. Nesse contexto foram determinados diferentes critérios de amostragem de solo com objetivo de estabelecer dentre eles o mais eficaz, sendo esses constituídos por: a) três amostras simples; b) duas amostras compostas advindas de cinco simples; c) duas amostras compostas advindas de dez simples e d) duas amostras compostas advindas de vinte simples em uma área homogênea de 250m2. Utilizou-se para remoção das amostras a pá de corte e um trado de caneca com profundidade de 20 cm, em um Argissolo Vermelho Distrófico Úmbrico, situado no município de Guarabira - PB. |
|
Palavras-Chave: |
Macronutrientes; Macronutrients. |
|
Thesagro: |
Argissolos; Conservação do Solo; Degradação Ambiental; Fertilidade do Solo. |
|
Thesaurus NAL: |
Environmental degradation; Soil conservation; Soil degradation; Soil fertility. |
|
Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1152224/1/ANALISE-ARGISSOLO-GUARABIRA.pdf
|
|
Marc: |
LEADER 01758nam a2200289 a 4500
001 2152224
005 2023-03-12
008 2011 bl uuuu u00u1 u #d
100 1 $aALMEIDA, C. A. de
245 $aAnálise de argissolo para fins de fertilidade em função de critérios de amostragem e do instrumento de coleta das amostras no município de Guarabira - PB.$h[electronic resource]
260 $aIn: CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 33., 2011, Uberlândia. Solo nos biomas brasileiros: sustentabilidade e mudanças climáticas: anais. [Uberlândia]: SBCS: UFU: ICIAG, 2011. 1 CD-ROM.$c2011
300 $a4 p.
520 $aA utilização da análise química na prática do manejo agrícola é imprescindível. Nesse contexto foram determinados diferentes critérios de amostragem de solo com objetivo de estabelecer dentre eles o mais eficaz, sendo esses constituídos por: a) três amostras simples; b) duas amostras compostas advindas de cinco simples; c) duas amostras compostas advindas de dez simples e d) duas amostras compostas advindas de vinte simples em uma área homogênea de 250m2. Utilizou-se para remoção das amostras a pá de corte e um trado de caneca com profundidade de 20 cm, em um Argissolo Vermelho Distrófico Úmbrico, situado no município de Guarabira - PB.
650 $aEnvironmental degradation
650 $aSoil conservation
650 $aSoil degradation
650 $aSoil fertility
650 $aArgissolos
650 $aConservação do Solo
650 $aDegradação Ambiental
650 $aFertilidade do Solo
653 $aMacronutrientes
653 $aMacronutrients
700 1 $aREINALDO, L. R. L. R.
700 1 $aARRUDA, L. V. de
700 1 $aFERREIRA, D. R. F.
700 1 $aSANTOS, J. W. dos
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Algodão (CNPA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
