Data/hora: 07/06/2024 09:34:31

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 25/07/2008
Data da última atualização: | 11/03/2024
Autoria: | FELICIO, L. F.; FLORIO, J. C.; SIDER, L. H.; CRUZ-CASALLA, P. E.; BRIDGES, R. S.
Título: | Reproductive experience increases striatal and hypothalamic dopamine levels in pregnant rats.
Ano de publicação: | 1996
Fonte/Imprenta: | Brain Research Bulletin, v. 40, n. v, p. 253-256, 1996.
Idioma: | Inglês
Conteúdo: | The effects of parity on the dopaminergic function of rats were studied. Striatal and hypothalamic levels of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), norepinephrine (NE), serotonin (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) as well as serum prolactin (PRL) levels of 7-days primigravid and multigravid rats were compared. Brains and trunk blood were collected from 1200-1400 h on day 7 of pregnancy and assayed for monoamines and their metabolites, and prolacUn, respectively. Multigravid rats showed a significant increase in striatal and hypothalamic dopamine levels. A tendency to increase in striatal DOPAC levels was also observed in multigravid rats. Levels of other neurotransmitters and metabolites were not statistically different. Haloperidol (1 mg/kg) treatment induced a significant increase in multigravid 5-HT striatal levels. There was no statistical difference among primigrevid and multigravid serum PRL levels after either saline or haloperidol treatment. These data suggest that prior parity produces a shift in dopaminergic activity in multigravid rats.
Palavras-Chave: | Dopamina; Hipotálamo.
Thesagro: | Hormônio; Parto; Prolactina; Reprodução Animal.
Categoria do assunto: | --
Registro original: | Embrapa Caprinos e Ovinos (CNPC)

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