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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
21/11/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
ABDALLA, S. L.; COSTA, S. S.; GIOSO, M. A.; CASANOVA, L. M.; COUTINHO, M. A. S.; SILVA, M. F. A.; BOTELHO, M. C. da S. N.; DIAS, R. S. G. |
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Afiliação: |
Samira L. Abdalla, Departamento de Cirurgia/Faculdade de Medicina Veterinária e Zootecnia/Universidade de São Paulo -USP; Sônia S. Costa, Instituto de Pesquisas de Produtos Naturais/Universidade Federal do Rio de Janeiro - UFRJ; Marco Antônio Gioso, Departamento de Cirurgia/Faculdade de Medicina Veterinária e Zootecnia/Universidade de São Paulo -USP; Livia M. Casanova, Instituto de Pesquisas de Produtos Naturais/Universidade Federal do Rio de Janeiro - UFRJ; Marcela A. S. Coutinho, Instituto de Pesquisas de Produtos Naturais/Universidade Federal do Rio de Janeiro - UFRJ; Marta Fernanda A. Silva, Departamento de Medicina e Cirurgia/Universidade Federal Rural do Rio de Janeiro - UFRRJ; Maria Clara da S. N. Botelho, Departamento de Parasitologia Animal/UFRRJ; Raquel S. G. Dias, Programa de Ciência Cardiovascular/Faculdade de Medicina/Universidade Federal Fluminense - UFF. |
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Título: |
Efficacy of a Kalanchoe gastonis-bonnieri extract to control bacterial biofilms and dental calculus in dogs. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 8, p. 859-865, ago. 2017. |
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Idioma: |
Inglês |
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Notas: |
Título em português: Eficácia do extrato de Kalanchoe gastonis-bonnieri no controle do biofilme bacteriano e cálculo dentário em cães. |
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Conteúdo: |
An aqueous leaf extract of the medicinal species Kalanchoe gastonis-bonnieri (here denominated KGB) has been found to be effective as an antimicrobial agent against canine oral cavity bacteria in in vitro assays. In this study, we investigated the effect of topic oral administration of KGB on the development of dental biofilm in Beagle dogs. The experiments were performed with an experimental group (0.2% of KGB extract), a negative control group (0.9% of saline solution) and a positive control group (0.12% chlorhexidine). Each treatment was sprayed into the oral cavity daily for 28 days. Thirty Beagle dogs with similar characteristics and kept under the same management and diet were used. The measurement of dental plaque and calculus was performed using a computerized analytical method. The phenolic profile of KGB extract was analyzed by HPLC-DAD. KGB extract at 0.2% showed efficacy in controlling the formation of plaque compared to the negative control group, and dental calculus in relation to the negative and positive control groups. A significant difference was observed among these three groups. Peaks attributed to flavonoids and phenolic acids were identified in the HPLC-DAD chromatogram of the KGB extract. The presence of these substances could be related to the activity observed. Our findings demonstrate that treatment with KGB is effective in controlling periodontal disease in dogs, providing new insights into the medicinal properties of this plant. KGB extract has a potential use as a supplemental agent in pharmaceutical products for the prevention of periodontal disease. MenosAn aqueous leaf extract of the medicinal species Kalanchoe gastonis-bonnieri (here denominated KGB) has been found to be effective as an antimicrobial agent against canine oral cavity bacteria in in vitro assays. In this study, we investigated the effect of topic oral administration of KGB on the development of dental biofilm in Beagle dogs. The experiments were performed with an experimental group (0.2% of KGB extract), a negative control group (0.9% of saline solution) and a positive control group (0.12% chlorhexidine). Each treatment was sprayed into the oral cavity daily for 28 days. Thirty Beagle dogs with similar characteristics and kept under the same management and diet were used. The measurement of dental plaque and calculus was performed using a computerized analytical method. The phenolic profile of KGB extract was analyzed by HPLC-DAD. KGB extract at 0.2% showed efficacy in controlling the formation of plaque compared to the negative control group, and dental calculus in relation to the negative and positive control groups. A significant difference was observed among these three groups. Peaks attributed to flavonoids and phenolic acids were identified in the HPLC-DAD chromatogram of the KGB extract. The presence of these substances could be related to the activity observed. Our findings demonstrate that treatment with KGB is effective in controlling periodontal disease in dogs, providing new insights into the medicinal properties of this plant. KGB extract has a ... Mostrar Tudo |
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Palavras-Chave: |
Bacterial biofilm; Biofilme bacteriano; Cálculo dentário; Dental plaque; Doença periodontal; Extrato de planta; Periodontal disease; Placa bacteriana; Plant Extract. |
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Thesagro: |
Cão; Flavonoide. |
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Thesaurus Nal: |
Dental calculus; Dogs; Flavonoids. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/167069/1/Efficacy-of-kalanchoe-gastonis-bonnieri.pdf
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Marc: |
LEADER 02864naa a2200385 a 4500
001 2080206
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aABDALLA, S. L.
245 $aEfficacy of a Kalanchoe gastonis-bonnieri extract to control bacterial biofilms and dental calculus in dogs.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Eficácia do extrato de Kalanchoe gastonis-bonnieri no controle do biofilme bacteriano e cálculo dentário em cães.
520 $aAn aqueous leaf extract of the medicinal species Kalanchoe gastonis-bonnieri (here denominated KGB) has been found to be effective as an antimicrobial agent against canine oral cavity bacteria in in vitro assays. In this study, we investigated the effect of topic oral administration of KGB on the development of dental biofilm in Beagle dogs. The experiments were performed with an experimental group (0.2% of KGB extract), a negative control group (0.9% of saline solution) and a positive control group (0.12% chlorhexidine). Each treatment was sprayed into the oral cavity daily for 28 days. Thirty Beagle dogs with similar characteristics and kept under the same management and diet were used. The measurement of dental plaque and calculus was performed using a computerized analytical method. The phenolic profile of KGB extract was analyzed by HPLC-DAD. KGB extract at 0.2% showed efficacy in controlling the formation of plaque compared to the negative control group, and dental calculus in relation to the negative and positive control groups. A significant difference was observed among these three groups. Peaks attributed to flavonoids and phenolic acids were identified in the HPLC-DAD chromatogram of the KGB extract. The presence of these substances could be related to the activity observed. Our findings demonstrate that treatment with KGB is effective in controlling periodontal disease in dogs, providing new insights into the medicinal properties of this plant. KGB extract has a potential use as a supplemental agent in pharmaceutical products for the prevention of periodontal disease.
650 $aDental calculus
650 $aDogs
650 $aFlavonoids
650 $aCão
650 $aFlavonoide
653 $aBacterial biofilm
653 $aBiofilme bacteriano
653 $aCálculo dentário
653 $aDental plaque
653 $aDoença periodontal
653 $aExtrato de planta
653 $aPeriodontal disease
653 $aPlaca bacteriana
653 $aPlant Extract
700 1 $aCOSTA, S. S.
700 1 $aGIOSO, M. A.
700 1 $aCASANOVA, L. M.
700 1 $aCOUTINHO, M. A. S.
700 1 $aSILVA, M. F. A.
700 1 $aBOTELHO, M. C. da S. N.
700 1 $aDIAS, R. S. G.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 8, p. 859-865, ago. 2017.
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