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Registro Completo |
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
07/12/2015 |
Data da última atualização: |
26/01/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MOURA, A. S. A. M. T.; LEDUR, M. C.; BOSCHIERO, C.; NONES, K.; PINTO, L. F. B.; JAENISCH, F. R. F.; BURT, D. W.; COUTINHO, L. L. |
Afiliação: |
ANA SILVIA ALVES MEIRA TAVARES MOURA, UNESP/FMVZ; MONICA CORREA LEDUR, CNPSA; CLARISSA BOSCHIERO, ESALQ; KATIA NONES, QIMR Berghofer Medical Research Institute; LUÍS FERNANDO BATISTA PINTO, UFB/Departamento de Zootecnia; FATIMA REGINA FERREIRA JAENISCH, CNPSA; DAVID W. BURT, University of Edinburgh; LUIZ LEHMANN COUTINHO, ESALQ. |
Título: |
Quantitative trait loci with sex-specific effects for internal organs weights and hematocrit value in a broiler-layer cross. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
Journal of Applied Genetics, v. 57, n. 2, p. 215–224, 2015. |
DOI: |
10.1007/s13353-015-0325-2 |
Idioma: |
Inglês |
Conteúdo: |
Abstract Rapid growth in broilers is associated with susceptibility to metabolic disorders such as pulmonary hypertension syndrome (ascites) and sudden death. This study describes a genome search for QTL associated with relative weight of cardio respiratory and metabolically important organs (heart, lungs, liver and gizzard), and hematocrit value in a Brazilian broiler-layer cross. QTL with similar or different effects across sexes were investigated. At 42 days of age after fasted for 6 h, the F2 chickens were weighed and slaughtered. Weights and percentages of the weight relative to BW42 of gizzard, heart, lungs, liver and hematocrit were used in the QTL search. Parental, F1 and F2 individuals were genotyped with 128 genetic markers (127 microsatellites and 1 SNP) covering 22 linkage groups. QTL mapping analyses were carried out using mixed models. A total of 11 genome-wide significant QTL and five suggestive linkages were mapped. Thus, genomewide significant QTL with similar effects across sexes were mapped to GGA2, 4 and 14 for heart weight, and to GGA2, 8 and 12 for gizzard %. Additionally, five genome-wide significant QTL with different effects across sexes were mapped to GGA 8, 19 and 26 for heart weight; GGA26 for heart % and GGA3 for hematocrit value. Five QTL were detected in chromosomal regions where QTL for similar traits were previously mapped in other F2 chicken populations. Seven novel genome-wide significant QTL are reported here, and 21 positional candidate genes in QTL regions were identified. MenosAbstract Rapid growth in broilers is associated with susceptibility to metabolic disorders such as pulmonary hypertension syndrome (ascites) and sudden death. This study describes a genome search for QTL associated with relative weight of cardio respiratory and metabolically important organs (heart, lungs, liver and gizzard), and hematocrit value in a Brazilian broiler-layer cross. QTL with similar or different effects across sexes were investigated. At 42 days of age after fasted for 6 h, the F2 chickens were weighed and slaughtered. Weights and percentages of the weight relative to BW42 of gizzard, heart, lungs, liver and hematocrit were used in the QTL search. Parental, F1 and F2 individuals were genotyped with 128 genetic markers (127 microsatellites and 1 SNP) covering 22 linkage groups. QTL mapping analyses were carried out using mixed models. A total of 11 genome-wide significant QTL and five suggestive linkages were mapped. Thus, genomewide significant QTL with similar effects across sexes were mapped to GGA2, 4 and 14 for heart weight, and to GGA2, 8 and 12 for gizzard %. Additionally, five genome-wide significant QTL with different effects across sexes were mapped to GGA 8, 19 and 26 for heart weight; GGA26 for heart % and GGA3 for hematocrit value. Five QTL were detected in chromosomal regions where QTL for similar traits were previously mapped in other F2 chicken populations. Seven novel genome-wide significant QTL are reported here, and 21 positional candidate g... Mostrar Tudo |
Thesagro: |
Frango de corte; Melhoramento genético animal. |
Thesaurus Nal: |
Animal genetics; Broiler chickens; Genetic markers; Molecular genetics. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/134959/1/final8050.pdf
|
Marc: |
LEADER 02444naa a2200289 a 4500 001 2030756 005 2018-01-26 008 2015 bl uuuu u00u1 u #d 024 7 $a10.1007/s13353-015-0325-2$2DOI 100 1 $aMOURA, A. S. A. M. T. 245 $aQuantitative trait loci with sex-specific effects for internal organs weights and hematocrit value in a broiler-layer cross.$h[electronic resource] 260 $c2015 520 $aAbstract Rapid growth in broilers is associated with susceptibility to metabolic disorders such as pulmonary hypertension syndrome (ascites) and sudden death. This study describes a genome search for QTL associated with relative weight of cardio respiratory and metabolically important organs (heart, lungs, liver and gizzard), and hematocrit value in a Brazilian broiler-layer cross. QTL with similar or different effects across sexes were investigated. At 42 days of age after fasted for 6 h, the F2 chickens were weighed and slaughtered. Weights and percentages of the weight relative to BW42 of gizzard, heart, lungs, liver and hematocrit were used in the QTL search. Parental, F1 and F2 individuals were genotyped with 128 genetic markers (127 microsatellites and 1 SNP) covering 22 linkage groups. QTL mapping analyses were carried out using mixed models. A total of 11 genome-wide significant QTL and five suggestive linkages were mapped. Thus, genomewide significant QTL with similar effects across sexes were mapped to GGA2, 4 and 14 for heart weight, and to GGA2, 8 and 12 for gizzard %. Additionally, five genome-wide significant QTL with different effects across sexes were mapped to GGA 8, 19 and 26 for heart weight; GGA26 for heart % and GGA3 for hematocrit value. Five QTL were detected in chromosomal regions where QTL for similar traits were previously mapped in other F2 chicken populations. Seven novel genome-wide significant QTL are reported here, and 21 positional candidate genes in QTL regions were identified. 650 $aAnimal genetics 650 $aBroiler chickens 650 $aGenetic markers 650 $aMolecular genetics 650 $aFrango de corte 650 $aMelhoramento genético animal 700 1 $aLEDUR, M. C. 700 1 $aBOSCHIERO, C. 700 1 $aNONES, K. 700 1 $aPINTO, L. F. B. 700 1 $aJAENISCH, F. R. F. 700 1 $aBURT, D. W. 700 1 $aCOUTINHO, L. L. 773 $tJournal of Applied Genetics$gv. 57, n. 2, p. 215–224, 2015.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Registros recuperados : 50 | |
21. | | MOREIRA, G. C. M.; CESAR, A. S. M.; GODOY, T. F.; BOSCHIERO, C.; LEDUR, M. C.; GARRICK, D. J.; MOURA, A. S. A. M. T.; COUTINHO, L. L. Genome-wide association studies reveal genomic windows and candidate genes related to fat deposition in chickens. In: PLANT & ANIMAL GENOME CONFERENCE, 24., 2016, San Diego, CA. [Abstracts...]. San Diego: [s.n.], 2016. Pôster P0647.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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22. | | FELÍCIO, A. M.; BOSCHIERO, C.; BALIEIRO, J. C. C.; LEDUR, M. C.; FERRAZ J. B. S.; MICHELAN FILHO, T.; MOURA, A. S. A. M. T.; COUTINHO, L. L. Identification and association of polymorphisms in CAPN1 and CAP3 candidate genes related to performance and meat quality traits in chickens. Genetics and Molecular Research, Ribeirão Preto, v. 12, n. 1, p. 472-482, 2013.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Suínos e Aves. |
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23. | | GODOY, T. F.; MOREIRA, G. C. M.; SILVA, V. H.; BOSCHIERO, C.; LEDUR, M. C.; MOURA, A. S. A. M. T.; COUTINHO, L. L. Identification of CNVs on the genome of Brazilian chicken lines. In: PLANT & ANIMAL GENOME CONFERENCE, 24., 2016, San Diego, CA. [Abstracts...]. San Diego: [s.n.], 2016. Pôster P0646.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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24. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; LEDUR, M. C.; GASPARIN, G.; ANDRADE, S. C. da S.; PADUAN, M.; COUTINHO, L. L. Identification of mutations in a QTL region on chromosome 3 associated with fatness in chickens. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 38. ISAFG 2013. AB.31Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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25. | | GODOY, T. F.; MOREIRA, G. C. M.; BOSCHIERO, C.; LEDUR, M. C.; GASPARIN, G.; ANDRADE, S. C. da S.; PADUAN, M.; COUTINHO, L. L. Identification of polymorphisms in a QTL region on chicken chromosome 2 associated with muscle deposition. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 39. ISAFG 2013.AB.32Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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26. | | AMBO, M.; CAMPOS, R. de L. R.; MOURA, A. S. M. T.; BOSCHIERO, C.; ROSÁRIO, M. F. do; LEDUR, M. C.; NONES, K.; COUTINHO, L. L. Genetic linkage maps of chicken chromosomes 6, 7, 8, 11 and 13 from a brazilian resource population. Scientia Agrícola, v.65, n.5, p.447-452, 2008. Projeto/Plano de Ação: 01.02.102.10-10.Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - B |
Biblioteca(s): Embrapa Suínos e Aves. |
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27. | | ROSÁRIO, M. F.; LEDUR, M. C.; BOSCHIERO, C.; MOURA, A. S. A. M. T.; COUTINHO, L. L.; GARCIA, A. A. F. Mapeamento de QTLs para características de desempenho em galinhas. In: CONGRESSO LATINOAMERICANO DE AVICULTURA, 20., 2007, Porto Alegre. Memorias. Porto Alegre: UBA : FIERGS, 2007. p. 272-274. Projeto n. 01.02.10.210-10.Tipo: Artigo em Anais de Congresso / Nota Técnica | Circulação/Nível: -- - -- |
Biblioteca(s): Embrapa Suínos e Aves. |
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28. | | ROSÁRIO, M. F.; MARGARIDO, G. R. A.; BOSCHIERO, C.; NONES, K.; MOURA, A. S. A. M. T.; LEDUR, M. C.; COUTINHO, L. L.; GARCIA, A. A. F. Mapa consenso brasileiro do cromossomo 1 oriundo de cruzamentos recíprocos entre linhagens de corte e postura. In: CONFERÊNCIA FACTA DE CIÊNCIA E TECNOLOGIA AVÍCOLAS, 27., 2009, Porto Alegre. Anais [dos] trabalhos de pesquisa José Maria Lamas de Silva. [Campinas]: FACTA, 2009. Projeto/Plano de Ação: 01.02.10.210-10. Publicado em CD-ROM (CD00156).Tipo: Artigo em Anais de Congresso / Nota Técnica |
Biblioteca(s): Embrapa Suínos e Aves. |
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29. | | MOREIRA, G. C. M.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; GODOY, T. F.; PÉRTILLE, F.; LEDUR, M. C.; MOURA, A. S. A. M. T. M.; GARRICK, D. J.; COUTINHO, L. L. Integration of genome wide association studies and whole genome sequencing provides novel insights into fat deposition in chicken. Scientific Reports, v. 8, n. 16222, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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30. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; LEDUR, M. C.; GARRICK, D.; SILVA, V. H. da; CROOIJAMANS, R. P.; GROENEN, M. A. M.; COUTINHO, L. L. Integration of GWAS, CNV and sele ction signature reveals candidate genes for abdominal fat regulation in chickens. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland, New Zealand. Proceedings... Massey University, 2018. Digital Archive.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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31. | | BARON, E. E.; MOURA, A. S. A. M. T.; LEDUR, M. C.; PINTO, L. F. B.; BOSCHIERO, C.; RUY, D. C.; NONES, K.; ZANELLA, E. L.; ROSARIO, M. F. do; BURT, D. W.; COUTINHO, L. L. QTL for percentage of carcass and parts in a broiler x layer cross. Animal Genetics, 30 sep. 2010. Disponível em: . Acesso em: 22 fev 2011. Projeto/Plano de Ação: 02.07.60.700-01.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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32. | | AMBO, M.; MOURA, A. S. A. M. T.; LEDUR, M. C.; PINTO. L. F. B.; BARON, E. E.; RUY, D. C.; NONES, K.; CAMPOS, R. L. R.; BOSCHIERO, C.; BURT, D. W.; COUTINHO, L. L. Quantitative trait loci for performance traits in a broiler x layer cross Animal Genetics, v. 40, n. 2, p. 200-208, 2009. Disponível em: . Acesso em: 08 fev. 2010 Projeto/Plano de Ação: 01.02.102.10-10Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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33. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. Discovery of SNPs potentially associated with fatness in a QTL region on chicken chromosome 3. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: WCGALP: American Society of Animal Science, 2014.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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34. | | MOREIRA, G. C. M.; SALVIAN, M.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; GODOY, T. F.; LEDUR, M. C.; GARRICK, D.; MOURÃO, G. B.; COUTINHO, L. L. Genome-wide association scan for QTL and their positional candidate genes associated with internal organ traits in chickens. BMC Genomics, v. 20, n. 669, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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35. | | PERTILLE, F.; MOREIRA, G. C. M. M.; ZANELLA, R.; NUNES, J. de R. da S.; BOSCHIERO, C.; ROVADOSCKI, G. A.; MOURÃO, G. B.; LEDUR, M. C.; COUTINHO, L. L. Genome-wide association study for performance traits in chickens using genotype by sequencing approach. Scientific Reports, v. 7, n. 41748, 2017.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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36. | | MOREIRA, G. C. M.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; GODOY, T. F.; TREVISOLI, P. A.; CANTAO, M. E.; LEDUR, M. C.; IBELLI, A. M. G.; MOURA, A. S. M. T.; GARRICK, D.; COUTINHO, L. L. A genome-wide association study reveals novel genomic regions and positional candidate genes for fat deposition in broiler chickens. BMC Genomics, v. 19, n. 374, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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37. | | BOSCHIERO, C.; MOREIRA, G. C. M.; GHEYAS, A.; GODOY, T. F.; GASPARIN, G.; MARIANI, P. D. S. C.; PADUAN, M.; CESAR, A. S. M.; LEDUR, M. C.; COUTINHO, L. L. Genome-wide characterization of genetic variants and putative regions under selection in meat and egg-type chicken lines. BMC Genomics, v. 19, n. 83, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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38. | | ALMEIDA, O. A. C.; MOREIRA, G. C. M.; REZENDE, F. M.; BOSCHIERO, C.; PEIXOTO, J. de O.; IBELLI, A. M. G.; LEDUR, M. C.; NOVAIS, F. J. de; COUTINHO, L. L. Identification of selection signatures involved in performance traits in a paternal broiler line. BMC Genomics, v. 20, n. 449, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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39. | | TREVISOLI, P. A.; MOREIRA, G. C. M.; BOSCHIERO, C.; CESAR, A. S. M.; PETRINI, J.; MARGARIDO, G. R. A.; LEDUR, M. C.; MOURÃO, G. B.; GARRICK, D.; COUTINHO, L. L. A missense mutation in the MYBPH gene is associated with abdominal fat traits in meat-type chickens. Frontiers in Genetics, v. 12, n. 698163, 2021.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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40. | | NONES, K.; LEDUR, M. C.; MOURA, A. S. M. T.; BOSCHIERO, C.; PINTO, L. F. B.; RUY, D. C.; BARON, E. E.; CAMPOS, R. L. R.; AMBO, M.; ZANELLA, E. L.; COUTINHO, L. L. Mapeamento de QTL para características de produção e qualidade da carcaça em aves. Concórdia: Embrapa Suínos e Aves, 2009. p. 65-78Tipo: Capítulo em Livro Técnico-Científico |
Biblioteca(s): Embrapa Suínos e Aves. |
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Registros recuperados : 50 | |
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