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Registro Completo |
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
09/05/2012 |
Data da última atualização: |
16/02/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CALA, A. C.; CHAGAS, A. C. de S.; OLIVEIRA, M. C. de S.; MATOS, A. P.; BORGES, L. M. F.; SOUSA, L. A. D.; SOUZA, F. A.; OLIVEIRA, G. P. |
Afiliação: |
A. C. CALA, INSTITUTO DE INVESTIGACÃO AGRÁRIA DE MOÇAMBIQUE/MOCAMBIQUE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE; A. P. MATOS, Centro Universitário Central Paulista; L.M.F. BORGES, Universidade Federal de Goiás; L.A.D. SOUSA, Universidade Federal de Goiás; F. A. SOUZA, Universidade Estadual Paulista; G. P. OLIVEIRA, Universidade Estadual Paulista. |
Título: |
In vitro anthelmintic effect of Melia azedarach L. and Trichilia claussenii C. against sheep gastrointestinal nematodes. |
Ano de publicação: |
2012 |
Fonte/Imprenta: |
Experimental Parasitology, v. 130, n. 2, feb. 2012. |
Páginas: |
p. 98-102. |
DOI: |
10.1016/j.exppara.2011.12.011 |
Idioma: |
Inglês |
Conteúdo: |
The control of parasitic diseases in small ruminants is mainly done with the use of synthetic anthelmintics. However, incorrect and indiscriminate use of these products has caused the emergence of parasite resistance. Plants with anthelmintic activity are used in folk veterinary medicine, but it is necessary to investigate and scientifically validate low-cost phytotherapeutic alternatives for future use to control gastrointestinal nematodes in small ruminants by family farmers. Thus, the aim of this study was to evaluate the in vitro anthelmintic effect of plant extracts from Melia azedarach and Trichilia claussenii by the egg hatch test (EHT) and larval development test (LDT) against sheep gastrointestinal nematodes. The hexane extract of M. azedarach fruits was extracted through cold percolation and the methanol extract of T. claussenii leaves was obtained by extraction at room temperature in solvents in order of increasing polarity. The efficacy results were analyzed using the Probit program of SAS. The M. azedarach extract showed a LC50 of 572.2 lg/mL and LC99 of 1137.8 lg/mL in the EHT, and LC50 of 0.7 lg/mL and LC99 of 60.8 lg/mL in the LDT. In turn, the T. claussenii extract presented a LC50 of 263.8 lg/mL and LC99 of 522.5 lg/mL in the EHT and LC50 of 1.1 lg/mL and LC99 of 26.4 lg/mL in the LDT. Comparing the extracts of the species from the Meliaceae family, T. claussenii showed greater anti-parasite potential in vitro than M. azedarach. However, studies on the isolated compounds, toxicity and administration forms to animals are also needed to validate low-cost alternative herbal remedies for use to control gastrointestinal nematodes by family farmers. MenosThe control of parasitic diseases in small ruminants is mainly done with the use of synthetic anthelmintics. However, incorrect and indiscriminate use of these products has caused the emergence of parasite resistance. Plants with anthelmintic activity are used in folk veterinary medicine, but it is necessary to investigate and scientifically validate low-cost phytotherapeutic alternatives for future use to control gastrointestinal nematodes in small ruminants by family farmers. Thus, the aim of this study was to evaluate the in vitro anthelmintic effect of plant extracts from Melia azedarach and Trichilia claussenii by the egg hatch test (EHT) and larval development test (LDT) against sheep gastrointestinal nematodes. The hexane extract of M. azedarach fruits was extracted through cold percolation and the methanol extract of T. claussenii leaves was obtained by extraction at room temperature in solvents in order of increasing polarity. The efficacy results were analyzed using the Probit program of SAS. The M. azedarach extract showed a LC50 of 572.2 lg/mL and LC99 of 1137.8 lg/mL in the EHT, and LC50 of 0.7 lg/mL and LC99 of 60.8 lg/mL in the LDT. In turn, the T. claussenii extract presented a LC50 of 263.8 lg/mL and LC99 of 522.5 lg/mL in the EHT and LC50 of 1.1 lg/mL and LC99 of 26.4 lg/mL in the LDT. Comparing the extracts of the species from the Meliaceae family, T. claussenii showed greater anti-parasite potential in vitro than M. azedarach. However, studies on the isol... Mostrar Tudo |
Palavras-Chave: |
Control Phytotherapy; EHT; LDT. |
Thesagro: |
Haemonchus Contortus. |
Thesaurus Nal: |
sheep. |
Categoria do assunto: |
H Saúde e Patologia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/924240/1/VitroAnthelminticEffect.pdf
|
Marc: |
LEADER 02548naa a2200289 a 4500 001 1924240 005 2023-02-16 008 2012 bl uuuu u00u1 u #d 024 7 $a10.1016/j.exppara.2011.12.011$2DOI 100 1 $aCALA, A. C. 245 $aIn vitro anthelmintic effect of Melia azedarach L. and Trichilia claussenii C. against sheep gastrointestinal nematodes.$h[electronic resource] 260 $c2012 300 $ap. 98-102. 520 $aThe control of parasitic diseases in small ruminants is mainly done with the use of synthetic anthelmintics. However, incorrect and indiscriminate use of these products has caused the emergence of parasite resistance. Plants with anthelmintic activity are used in folk veterinary medicine, but it is necessary to investigate and scientifically validate low-cost phytotherapeutic alternatives for future use to control gastrointestinal nematodes in small ruminants by family farmers. Thus, the aim of this study was to evaluate the in vitro anthelmintic effect of plant extracts from Melia azedarach and Trichilia claussenii by the egg hatch test (EHT) and larval development test (LDT) against sheep gastrointestinal nematodes. The hexane extract of M. azedarach fruits was extracted through cold percolation and the methanol extract of T. claussenii leaves was obtained by extraction at room temperature in solvents in order of increasing polarity. The efficacy results were analyzed using the Probit program of SAS. The M. azedarach extract showed a LC50 of 572.2 lg/mL and LC99 of 1137.8 lg/mL in the EHT, and LC50 of 0.7 lg/mL and LC99 of 60.8 lg/mL in the LDT. In turn, the T. claussenii extract presented a LC50 of 263.8 lg/mL and LC99 of 522.5 lg/mL in the EHT and LC50 of 1.1 lg/mL and LC99 of 26.4 lg/mL in the LDT. Comparing the extracts of the species from the Meliaceae family, T. claussenii showed greater anti-parasite potential in vitro than M. azedarach. However, studies on the isolated compounds, toxicity and administration forms to animals are also needed to validate low-cost alternative herbal remedies for use to control gastrointestinal nematodes by family farmers. 650 $asheep 650 $aHaemonchus Contortus 653 $aControl Phytotherapy 653 $aEHT 653 $aLDT 700 1 $aCHAGAS, A. C. de S. 700 1 $aOLIVEIRA, M. C. de S. 700 1 $aMATOS, A. P. 700 1 $aBORGES, L. M. F. 700 1 $aSOUSA, L. A. D. 700 1 $aSOUZA, F. A. 700 1 $aOLIVEIRA, G. P. 773 $tExperimental Parasitology$gv. 130, n. 2, feb. 2012.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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Biblioteca(s): |
Embrapa Cerrados. |
Data corrente: |
07/06/2004 |
Data da última atualização: |
28/10/2009 |
Autoria: |
MELO, J. T. de; RESCK. D. V. S. |
Título: |
Retorno, ao solo, de nutrientes de serrapilheira de pinus no cerrado do Distrito Federal. |
Ano de publicação: |
2002 |
Fonte/Imprenta: |
Planaltina: Embrapa Cerrados, 2002. |
Páginas: |
18 p. |
Série: |
(Embrapa Cerrados. Boletim de Pesquisa e Desenvolvimento, 75). |
Idioma: |
Português |
Notas: |
CRI6550 |
Palavras-Chave: |
Carbono organico; Ciclagem; Cycling; Pinus caribea. |
Thesagro: |
Cerrado; Fertilidade do Solo; Matéria Orgânica; Nutriente; Reflorestamento; Serapilheira. |
Thesaurus NAL: |
carbon; nutrients; organic matter; reforestation; soil fertility. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/CPAC-2009/24656/1/bolpd_75.pdf
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Marc: |
LEADER 00902nam a2200325 a 4500 001 1559118 005 2009-10-28 008 2002 bl uuuu u0uu1 u #d 100 1 $aMELO, J. T. de 245 $aRetorno, ao solo, de nutrientes de serrapilheira de pinus no cerrado do Distrito Federal. 260 $aPlanaltina: Embrapa Cerrados$c2002 300 $a18 p. 490 $a(Embrapa Cerrados. Boletim de Pesquisa e Desenvolvimento, 75). 500 $aCRI6550 650 $acarbon 650 $anutrients 650 $aorganic matter 650 $areforestation 650 $asoil fertility 650 $aCerrado 650 $aFertilidade do Solo 650 $aMatéria Orgânica 650 $aNutriente 650 $aReflorestamento 650 $aSerapilheira 653 $aCarbono organico 653 $aCiclagem 653 $aCycling 653 $aPinus caribea 700 1 $aRESCK. D. V. S.
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