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Registro Completo |
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
12/01/2023 |
Data da última atualização: |
10/02/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
SILVA, G de S.; CASTRO, C. D. P. da C.; BORGES, G da S. C.; FREITAS, S. T. de; AIDAR, S. de T.; BIASOTO, A. C. T.; RYBKA, A. C. P.; CARDARELLI, H. R. |
Afiliação: |
GRACIETE DE SOUZA SILVA, UNIVERSIDADE FEDERAL DA PARAÍBA; CLIVIA DANUBIA PINHO DA C CASTRO, CPATSA; GRACIELE DA SILVA CAMPELO BORGES, UNIVERSIDADE FEDERAL DA PELOTAS; SERGIO TONETTO DE FREITAS, CPATSA; SAULO DE TARSO AIDAR, CPATSA; ALINE TELLES BIASOTO MARQUES, CNPMA; ANA CECILIA POLONI RYBKA, CPATSA; HAÍSSA ROBERTA CARDARELLI, UNIVERSIDADE FEDERAL DA PARAÍBA. |
Título: |
Physicochemical and functional properties of new sports drink with ricotta cheese whey and a brazilian passion fruit variety. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Journal of Food Science and Technology, v. 60, n. 2, p. 538-548, 2023. |
ISSN: |
0975-8402 |
DOI: |
https://doi.org/10.1007/s13197-022-05636-5 |
Idioma: |
Inglês |
Conteúdo: |
aBSTRACT: The present study investigated the bioaccessibility of minerals, bioactive compounds, and sensory acceptance of isotonic beverages formulated with Ricotta cheese whey (RCW) and passion fruit cv. BRS Sertão Forte. Three formulations were developed: I1 with 50% RCW and 5% passion fruit pulp, I2 with 50% RCW and 8.5% pulp, and I3 with 30% RCW and 12% pulp. I3 showed higher ascorbic acid content and antioxidant activity, exhibited the highest scores in the consumer test, and maintained its physicochemical stability and microbiological safety during the storage at 7 °C for 56 days. (?)-Epicatechin gallate, (?)-epigallocatechin gallate, and cis-resveratrol were the main phenolic compounds quantified in the isotonic beverages. I1 and I3 exhibited high bioaccessibility of the minerals K, Na, and Mg (37?70%) compared to I2, which showed bioaccessibility between 31 and 40%. The beverages developed are innovative alternatives for the market of supplements for athletes, combining the use of a dairy industry by-product and a new variety of passion fruit to date little-explored economically. |
Thesagro: |
Bebida não Alcoólica; Maracujá; Ricota; Soro de Leite; Suplemento Energético. |
Thesaurus Nal: |
Bioactive compounds; Cheese whey; In vitro digestion; Passion fruits; Physicochemical properties; Sensory evaluation; Sports drinks. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
Marc: |
LEADER 02274naa a2200373 a 4500 001 2150906 005 2023-02-10 008 2022 bl uuuu u00u1 u #d 022 $a0975-8402 024 7 $ahttps://doi.org/10.1007/s13197-022-05636-5$2DOI 100 1 $aSILVA, G de S. 245 $aPhysicochemical and functional properties of new sports drink with ricotta cheese whey and a brazilian passion fruit variety.$h[electronic resource] 260 $c2022 520 $aaBSTRACT: The present study investigated the bioaccessibility of minerals, bioactive compounds, and sensory acceptance of isotonic beverages formulated with Ricotta cheese whey (RCW) and passion fruit cv. BRS Sertão Forte. Three formulations were developed: I1 with 50% RCW and 5% passion fruit pulp, I2 with 50% RCW and 8.5% pulp, and I3 with 30% RCW and 12% pulp. I3 showed higher ascorbic acid content and antioxidant activity, exhibited the highest scores in the consumer test, and maintained its physicochemical stability and microbiological safety during the storage at 7 °C for 56 days. (?)-Epicatechin gallate, (?)-epigallocatechin gallate, and cis-resveratrol were the main phenolic compounds quantified in the isotonic beverages. I1 and I3 exhibited high bioaccessibility of the minerals K, Na, and Mg (37?70%) compared to I2, which showed bioaccessibility between 31 and 40%. The beverages developed are innovative alternatives for the market of supplements for athletes, combining the use of a dairy industry by-product and a new variety of passion fruit to date little-explored economically. 650 $aBioactive compounds 650 $aCheese whey 650 $aIn vitro digestion 650 $aPassion fruits 650 $aPhysicochemical properties 650 $aSensory evaluation 650 $aSports drinks 650 $aBebida não Alcoólica 650 $aMaracujá 650 $aRicota 650 $aSoro de Leite 650 $aSuplemento Energético 700 1 $aCASTRO, C. D. P. da C. 700 1 $aBORGES, G da S. C. 700 1 $aFREITAS, S. T. de 700 1 $aAIDAR, S. de T. 700 1 $aBIASOTO, A. C. T. 700 1 $aRYBKA, A. C. P. 700 1 $aCARDARELLI, H. R. 773 $tJournal of Food Science and Technology$gv. 60, n. 2, p. 538-548, 2023.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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Registro Completo
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
21/02/2022 |
Data da última atualização: |
08/04/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
BARON, L. F.; FONSECA, F. M. da; MACIAG, S. S.; BELLAVER, F. A. V.; IBELLI, A. M. G.; MORES, M. A. Z.; ALMEIDA, G. F. de; GUTERRES, S. S.; BASTOS, A. P. A.; PAESE, K. |
Afiliação: |
LANA FLÁVIA BARON, UFRGS; FRANCISCO NOE DA FONSECA, CNPSA; SHAIANA SALETE MACIAG, Unicentro/Guarapuava; FRANCIANA A VOLPATO BELLAVER, IFC/Concórdia; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; GABRYELLE FURTADO DE ALMEIDA, UFRGS; SILVIA STANIÇUASKI GUTERRES, UFRGS; ANA PAULA ALMEIDA BASTOS, CNPSA; KARINA PAESE, UFRGS. |
Título: |
Toltrazuril-loaded polymeric nanocapsules as a promising approach for the preventive control of coccidiosis in poultry. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Pharmaceutics, v. 14, n. 392, 2022. |
DOI: |
https://doi.org/10.3390/pharmaceutics14020392 |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Coccidiosis is a disease caused by intracellular protozoan parasites of the genus Eimeria that affect the intestinal tract of poultry. However, strain resistance and drug residue in the carcass have drawn the attention of the productive sector. The nanotechnology can improve the biological effect of drugs, reducing of administered doses and toxic effects. Due to this, toltrazuril-load polymeric nanoparticles based on Eudragit® S100 (NCt) or poly-?-caprolactone (LNCt) were developed to prevent coccidiosis in broilers. Nanoformulations were produced and showed homogeneous particle diameter distribution in the nanometer range (z-average and D (4.3) < 200 nm), negative zeta potential (8.93 mV), drug content ~100%, and encapsulation efficiency >90%. Cell viability assays using avian fibroblasts showed that LNCt presented no relevant toxicity up to 72 h. LNCt was then prophylactically administrated to chicken followed by challenge with Eimeria oocysts. The evaluation of the small intestine and cecum showed that the treatment with LNCt (3.5 mg/kg/day) in drinking water reduced the lesion scores and oocysts excretion, similar to the reference medicine containing toltrazuril (Baycox®, 7 mg/kg/day). The current study shows the potential protective use of nanoencapsulating anticoccidial drugs as a promising approach for the control of coccidiosis in poultry. Resumo: A coccidiose é uma doença causada por parasitas protozoários intracelulares do gênero Eimeria que acometem o trato intestinal de aves. No entanto, a resistência à cepa e o resíduo de drogas na carcaça têm chamado a atenção do setor produtivo. A nanotecnologia pode melhorar o efeito biológico dos fármacos, reduzindo as doses administradas e os efeitos tóxicos. Devido a isso, nanopartículas poliméricas com carga de toltrazuril à base de Eudragit ® S100 (NCt) ou poli-ε-caprolactona (LNCt) foram desenvolvidas para prevenir a coccidiose em frangos de corte. Nanoformulações foram produzidas e apresentaram distribuição homogênea do diâmetro das partículas na faixa nanométrica ( z-média e D (4,3) < 200 nm), potencial zeta negativo (<-8,93 mV), teor de droga ~ 100% e eficiência de encapsulamento > 90%. Ensaios de viabilidade celular utilizando fibroblastos de aves mostraram que LNCt não apresentou toxicidade relevante até 72 h. LNCt foi então administrado profilaticamente ao frango seguido de desafio com oocistos de Eimeria . A avaliação do intestino delgado e ceco mostrou que o tratamento com LNCt (3,5 mg/kg/dia) na água de beber reduziu os escores de lesão e a excreção de oocistos, semelhante ao medicamento de referência contendo toltrazuril (Baycox ® , 7 mg/kg/dia ). O presente estudo mostra o potencial uso protetor de drogas anticoccidianas nanoencapsuladas como uma abordagem promissora para o controle da coccidiose em aves. MenosAbstract: Coccidiosis is a disease caused by intracellular protozoan parasites of the genus Eimeria that affect the intestinal tract of poultry. However, strain resistance and drug residue in the carcass have drawn the attention of the productive sector. The nanotechnology can improve the biological effect of drugs, reducing of administered doses and toxic effects. Due to this, toltrazuril-load polymeric nanoparticles based on Eudragit® S100 (NCt) or poly-?-caprolactone (LNCt) were developed to prevent coccidiosis in broilers. Nanoformulations were produced and showed homogeneous particle diameter distribution in the nanometer range (z-average and D (4.3) < 200 nm), negative zeta potential (8.93 mV), drug content ~100%, and encapsulation efficiency >90%. Cell viability assays using avian fibroblasts showed that LNCt presented no relevant toxicity up to 72 h. LNCt was then prophylactically administrated to chicken followed by challenge with Eimeria oocysts. The evaluation of the small intestine and cecum showed that the treatment with LNCt (3.5 mg/kg/day) in drinking water reduced the lesion scores and oocysts excretion, similar to the reference medicine containing toltrazuril (Baycox®, 7 mg/kg/day). The current study shows the potential protective use of nanoencapsulating anticoccidial drugs as a promising approach for the control of coccidiosis in poultry. Resumo: A coccidiose é uma doença causada por parasitas protozoários intracelulares do gênero Eimeria que acometem o ... Mostrar Tudo |
Palavras-Chave: |
Avian coccidiosis; Coccidiose aviária; Eimeria spp; Eudragit® S100; Nanocápsulas poliméricas; Poly-E-caprolactone; Polymeric nanocapsules. |
Thesaurus NAL: |
Toltrazuril. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/231608/1/final9854.pdf
|
Marc: |
LEADER 03923naa a2200337 a 4500 001 2140277 005 2022-04-08 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/pharmaceutics14020392$2DOI 100 1 $aBARON, L. F. 245 $aToltrazuril-loaded polymeric nanocapsules as a promising approach for the preventive control of coccidiosis in poultry.$h[electronic resource] 260 $c2022 520 $aAbstract: Coccidiosis is a disease caused by intracellular protozoan parasites of the genus Eimeria that affect the intestinal tract of poultry. However, strain resistance and drug residue in the carcass have drawn the attention of the productive sector. The nanotechnology can improve the biological effect of drugs, reducing of administered doses and toxic effects. Due to this, toltrazuril-load polymeric nanoparticles based on Eudragit® S100 (NCt) or poly-?-caprolactone (LNCt) were developed to prevent coccidiosis in broilers. Nanoformulations were produced and showed homogeneous particle diameter distribution in the nanometer range (z-average and D (4.3) < 200 nm), negative zeta potential (<?8.93 mV), drug content ~100%, and encapsulation efficiency >90%. Cell viability assays using avian fibroblasts showed that LNCt presented no relevant toxicity up to 72 h. LNCt was then prophylactically administrated to chicken followed by challenge with Eimeria oocysts. The evaluation of the small intestine and cecum showed that the treatment with LNCt (3.5 mg/kg/day) in drinking water reduced the lesion scores and oocysts excretion, similar to the reference medicine containing toltrazuril (Baycox®, 7 mg/kg/day). The current study shows the potential protective use of nanoencapsulating anticoccidial drugs as a promising approach for the control of coccidiosis in poultry. Resumo: A coccidiose é uma doença causada por parasitas protozoários intracelulares do gênero Eimeria que acometem o trato intestinal de aves. No entanto, a resistência à cepa e o resíduo de drogas na carcaça têm chamado a atenção do setor produtivo. A nanotecnologia pode melhorar o efeito biológico dos fármacos, reduzindo as doses administradas e os efeitos tóxicos. Devido a isso, nanopartículas poliméricas com carga de toltrazuril à base de Eudragit ® S100 (NCt) ou poli-ε-caprolactona (LNCt) foram desenvolvidas para prevenir a coccidiose em frangos de corte. Nanoformulações foram produzidas e apresentaram distribuição homogênea do diâmetro das partículas na faixa nanométrica ( z-média e D (4,3) < 200 nm), potencial zeta negativo (<-8,93 mV), teor de droga ~ 100% e eficiência de encapsulamento > 90%. Ensaios de viabilidade celular utilizando fibroblastos de aves mostraram que LNCt não apresentou toxicidade relevante até 72 h. LNCt foi então administrado profilaticamente ao frango seguido de desafio com oocistos de Eimeria . A avaliação do intestino delgado e ceco mostrou que o tratamento com LNCt (3,5 mg/kg/dia) na água de beber reduziu os escores de lesão e a excreção de oocistos, semelhante ao medicamento de referência contendo toltrazuril (Baycox ® , 7 mg/kg/dia ). O presente estudo mostra o potencial uso protetor de drogas anticoccidianas nanoencapsuladas como uma abordagem promissora para o controle da coccidiose em aves. 650 $aToltrazuril 653 $aAvian coccidiosis 653 $aCoccidiose aviária 653 $aEimeria spp 653 $aEudragit® S100 653 $aNanocápsulas poliméricas 653 $aPoly-E-caprolactone 653 $aPolymeric nanocapsules 700 1 $aFONSECA, F. M. da 700 1 $aMACIAG, S. S. 700 1 $aBELLAVER, F. A. V. 700 1 $aIBELLI, A. M. G. 700 1 $aMORES, M. A. Z. 700 1 $aALMEIDA, G. F. de 700 1 $aGUTERRES, S. S. 700 1 $aBASTOS, A. P. A. 700 1 $aPAESE, K. 773 $tPharmaceutics$gv. 14, n. 392, 2022.
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