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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
14/10/2004 |
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Data da última atualização: |
15/03/2017 |
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Autoria: |
HURTADO, A.; GARCÍA-PÉREZ, A. L; BELTRÁN de HEREDIA, I.; BARANDIKA, J.; SANZ-PARRA, A.; BERRIATUA, E.; JUSTE, R. A. |
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Título: |
Genetic susceptibility to scrapie in a population of Latxa breed sheep in the Basque Country, Spain. |
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Ano de publicação: |
2002 |
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Fonte/Imprenta: |
Small Ruminant Research, v. 45, n. 3, p. 255-259, 2002. |
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Idioma: |
Inglês |
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Conteúdo: |
Resistance to natural scrapie in sheep bas been associated with polymorphisms at codons 136, 154 and 171 of the prion protein (PrP). This study was undertaken to obtain preliminary information on the PrP gene-associated susceptibility to scrapie in the native sheep breed of the Spanish Basque Country (Latxa), where a single case of scrapie bas been reported. Six hundred and ninetyeight sheep from 10 commercial scrapie-free flocks were analysed. The genotype associated with a higher resistance (ARR/ARR) was present in 5.9%, whereas that associated with the highest susceptibility (homozygous VRQ) was absent. ical disease. ARQ/ARQ was the genotype most frequently observed (48.8%),indicating that susceptibile animals exist in the absence of clinicaldisease.This study provides base-line data for genotype frequencies of Latxa breed that can be included among the criteria used for breed selection to increase the frequencies of resistant genotypes without losing oout on productive characteristics. |
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Palavras-Chave: |
PrP genotyping; Spongiform encephalopathy. |
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Thesagro: |
Doença animal; Genótipo; Ovino; Peste de cocar; Sistema nervoso. |
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Thesaurus Nal: |
Nervous system diseases; Scrapie; Sheep. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01879naa a2200313 a 4500
001 1530758
005 2017-03-15
008 2002 bl uuuu u00u1 u #d
100 1 $aHURTADO, A.
245 $aGenetic susceptibility to scrapie in a population of Latxa breed sheep in the Basque Country, Spain.
260 $c2002
520 $aResistance to natural scrapie in sheep bas been associated with polymorphisms at codons 136, 154 and 171 of the prion protein (PrP). This study was undertaken to obtain preliminary information on the PrP gene-associated susceptibility to scrapie in the native sheep breed of the Spanish Basque Country (Latxa), where a single case of scrapie bas been reported. Six hundred and ninetyeight sheep from 10 commercial scrapie-free flocks were analysed. The genotype associated with a higher resistance (ARR/ARR) was present in 5.9%, whereas that associated with the highest susceptibility (homozygous VRQ) was absent. ical disease. ARQ/ARQ was the genotype most frequently observed (48.8%),indicating that susceptibile animals exist in the absence of clinicaldisease.This study provides base-line data for genotype frequencies of Latxa breed that can be included among the criteria used for breed selection to increase the frequencies of resistant genotypes without losing oout on productive characteristics.
650 $aNervous system diseases
650 $aScrapie
650 $aSheep
650 $aDoença animal
650 $aGenótipo
650 $aOvino
650 $aPeste de cocar
650 $aSistema nervoso
653 $aPrP genotyping
653 $aSpongiform encephalopathy
700 1 $aGARCÍA-PÉREZ, A. L
700 1 $aBELTRÁN de HEREDIA, I.
700 1 $aBARANDIKA, J.
700 1 $aSANZ-PARRA, A.
700 1 $aBERRIATUA, E.
700 1 $aJUSTE, R. A.
773 $tSmall Ruminant Research$gv. 45, n. 3, p. 255-259, 2002.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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