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 | Acesso ao texto completo restrito à biblioteca da Embrapa Soja. Para informações adicionais entre em contato com valeria.cardoso@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Soja. |
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Data corrente: |
25/10/2012 |
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Data da última atualização: |
26/07/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
HAGEN, M. K.; LUDKE, A.; ARAUJO, A. S.; MENDES, R. H.; FERNANDES, T. G.; MANDARINO, J. M. G.; LLESUY, S.; JONG, E. V. de; BELLÓ-KLEIN, A. |
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Afiliação: |
MARTINE KIENZLE HAGEN, UFRGS; ANA LUDKE, University of Manitoba; ALEX SANDER ARAUJO, UFRGS; ROBERTA HACK MENDES, UFRGS; TÂNIA GATELLI FERNANDES, UFRGS; JOSE MARCOS GONTIJO MANDARINO, CNPSO; SUSANA LLESUY, Universidade de Buenos Aires; ERNA VOGT DE JONG, UFRGS; ADRIANE BELLÓ-KLEIN, UFRGS. |
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Título: |
Antioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Canadian Journal of Physiology and Pharmacology, Ottawa, v. 90, n. 8, p. 1095-1103, 2012. |
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DOI: |
10.1139/y2012-028 |
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Idioma: |
Inglês |
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Conteúdo: |
This study analyzed and compared the content of isoflavones in 2 soy products, the effectiveness of isoflavones as antioxidants, in vitro, and demonstrated the antioxidant effect of a soy diet in rats with myocardial infarction (MI). Isoflavone content was analyzed in soybean hypocotyl (SH) and isolated soy protein (ISP). The quality (TAR) and quantity (TRAP) of antioxidants present in the samples was quantified. The amount of daidzin was higher in SH (9 times) and genistein in ISP (5 times). SH presented a 3-fold increase in TAR, while both products exhibited same TRAP. The rats were fed an ISP diet for 9 weeks. Animals were distributed among 6 treatment groups: (i) Sham Casein; (ii) Infarct Casein < 25%; (iii) Infarct Casein > 25%; (iv) Sham Soy; (v) Infarct Soy < 25%; and (vi) Infarct Soy > 25%. MI was induced 5 weeks after the commencement of the diets. Lipid peroxidation (LPO), antioxidant enzyme activity, and levels of nitrites/nitrates were determined in blood. Rats receiving the ISP diet demonstrated increased activity of antioxidant enzyme activity and nitrite/nitrate content. In addition, the increase in LPO seen in rats subjected to MI was significantly mitigated when the ISP diet was given. These findings suggest a nutritional approach of using a soy-based diet for the prevention of oxidative-stress-related diseases such as heart failure. |
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Thesagro: |
Antioxidante; Enzima; Lipidio; Peroxidase; Proteína; Soja. |
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Thesaurus Nal: |
Lipid peroxidation; Nitric oxide; Plant proteins; Soybeans. |
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Categoria do assunto: |
W Química e Física |
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Marc: |
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008 2012 bl uuuu u00u1 u #d
024 7 $a10.1139/y2012-028$2DOI
100 1 $aHAGEN, M. K.
245 $aAntioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model.
260 $c2012
520 $aThis study analyzed and compared the content of isoflavones in 2 soy products, the effectiveness of isoflavones as antioxidants, in vitro, and demonstrated the antioxidant effect of a soy diet in rats with myocardial infarction (MI). Isoflavone content was analyzed in soybean hypocotyl (SH) and isolated soy protein (ISP). The quality (TAR) and quantity (TRAP) of antioxidants present in the samples was quantified. The amount of daidzin was higher in SH (9 times) and genistein in ISP (5 times). SH presented a 3-fold increase in TAR, while both products exhibited same TRAP. The rats were fed an ISP diet for 9 weeks. Animals were distributed among 6 treatment groups: (i) Sham Casein; (ii) Infarct Casein < 25%; (iii) Infarct Casein > 25%; (iv) Sham Soy; (v) Infarct Soy < 25%; and (vi) Infarct Soy > 25%. MI was induced 5 weeks after the commencement of the diets. Lipid peroxidation (LPO), antioxidant enzyme activity, and levels of nitrites/nitrates were determined in blood. Rats receiving the ISP diet demonstrated increased activity of antioxidant enzyme activity and nitrite/nitrate content. In addition, the increase in LPO seen in rats subjected to MI was significantly mitigated when the ISP diet was given. These findings suggest a nutritional approach of using a soy-based diet for the prevention of oxidative-stress-related diseases such as heart failure.
650 $aLipid peroxidation
650 $aNitric oxide
650 $aPlant proteins
650 $aSoybeans
650 $aAntioxidante
650 $aEnzima
650 $aLipidio
650 $aPeroxidase
650 $aProteína
650 $aSoja
700 1 $aLUDKE, A.
700 1 $aARAUJO, A. S.
700 1 $aMENDES, R. H.
700 1 $aFERNANDES, T. G.
700 1 $aMANDARINO, J. M. G.
700 1 $aLLESUY, S.
700 1 $aJONG, E. V. de
700 1 $aBELLÓ-KLEIN, A.
773 $tCanadian Journal of Physiology and Pharmacology, Ottawa$gv. 90, n. 8, p. 1095-1103, 2012.
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Registro original: |
Embrapa Soja (CNPSO) |
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| Registros recuperados : 4 | |
| 2. |  | HAGEN, M. E. K.; MENDES, R. H.; FERNANDES, T. R. G.; MANDARINO, J. M. G.; BELLÓ-KLEIN, A. Análise da reatividade e do potencial antioxidante total e conteúdo de isoflavonas em proteína isolada de soja (Samprosoy) e gérmen de soja. In: CONGRESSO BRASILEIRO DE NUTRIÇÃO, 17.; CONGRESSO LATINO-AMERICANO, 2.; CONGRESSO BRASILEIRO DE NUTRIÇÃO HUMANA, 1., 2002, Porto Alegre. [Resumos]. Porto Alegre: ASBRAN; SBNC; AGAN, 2002. p. 150. Resumos A13/002.| Biblioteca(s): Embrapa Soja. |
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| 3. | | HAGEN, M. E. K.; MENDES, R. H.; FERNANDES, T. R.; BELLÓ-KLEIN, A.; MANDARINO, J. M. G. Efeito antioxidante da proteína de soja (Samprosoy LH 90) e germén de soja e sua relação com o conteudo de isoflavonas. In: CONGRESSO DE CARDIOLOGIA DO RIO GRANDE DO SUL, 13.; SIMPÓSIO DE NUTRIÇÃO EM CARDIOLOGIA, 1.; SIMPÓSIO DE FISIOTERAPIA EM CARDIOLOGIA, 1.; SIMPÓSIO DE ENFERMAGEM EM CARDIOLOGIA, 1., 2002, Gramado. Programa... Gramado, 2002. Não paginado. Seção Pôsteres número 6.| Biblioteca(s): Embrapa Soja. |
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| 4. | | HAGEN, M. K.; LUDKE, A.; ARAUJO, A. S.; MENDES, R. H.; FERNANDES, T. G.; MANDARINO, J. M. G.; LLESUY, S.; JONG, E. V. de; BELLÓ-KLEIN, A. Antioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model. Canadian Journal of Physiology and Pharmacology, Ottawa, v. 90, n. 8, p. 1095-1103, 2012.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Soja. |
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| Registros recuperados : 4 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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