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Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Milho e Sorgo. |
Data corrente: |
23/11/2011 |
Data da última atualização: |
28/09/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
RUIZ, J. C.; D'AFONSECA, V.; SILVA, A.; ALI, A.; PINTO, A. C.; SANTOS, A. R.; ROCHA, A. A. M. C.; LOPES, D. O.; DORELLA, F. A.; PACHECO, L. G. C.; COSTA, M. P.; TURK, M. Z.; SEYFFERT, N.; MORAES, P. M. R. O.; SOARES, S. C.; ALMEIDA, S. S.; CASTRO, T. L. P.; ABREU, V. A. C.; TROST, E.; BAUMBACH, J.; TAUCH, A.; SCHNEIDER, M. P. C.; McCULLOCH, J.; CERDEIRA, L. T.; RAMOS, R. T. J.; ZERLOTINI, A.; DOMINITINI, A.; RESENDE, D. M.; COSER, E. M.; OLIVEIRA, L. M.; PEDROSA, A. L.; VIEIRA, C. U.; GUIMARAES, C. T.; BARTHOLOMEU, D. C.; OLIVEIRA, D. M.; SANTOS, F. R.; RABELO, E. M.; LOBO, F. P.; FRANCO, G. R.; COSTA, A. F.; CASTRO, I. M.; DIAS, S. R. C.; FERRO, J. A.; ORTEGA, J. M.; PAIVA, L. V.; ALMEIDA, J. F.; GOULART, L. R.; FERRO, M. I. T.; CARNEIRO, N. P.; FALCÃO, P. R. K.; GRYNBERG, P.; TEIXEIRA, S. M. R.; BROMMONSCHENKEL, S.; OLIVEIRA, S. C.; MEYER, R.; MOORE, R. J.; MIYOSHI, A.; OLIVEIRA, G. C.; AZEVEDO, V. |
Afiliação: |
CLAUDIA TEIXEIRA GUIMARAES, CNPMS; NEWTON PORTILHO CARNEIRO, CNPMS. |
Título: |
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. |
Ano de publicação: |
2011 |
Fonte/Imprenta: |
Plos One, San Francisco, v. 6, n. 4, p. 1-16, 2011. |
DOI: |
10.1371/journal.pone.0018551 |
Idioma: |
Inglês |
Conteúdo: |
Background: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829. MenosBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal t... Mostrar Tudo |
Palavras-Chave: |
Análise de genoma; Genoma de C pseudotuberculosis; Ilhas de patogenicidade. |
Thesagro: |
Corynebacterium Pseudotuberculosis; Genética; Patógeno. |
Thesaurus Nal: |
Caseous lymphadenitis; Genome; Pathogenicity. |
Categoria do assunto: |
-- H Saúde e Patologia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/47474/1/Evidence-reductive.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/53621/1/journal.pone.0018551.pdf
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Marc: |
LEADER 04503naa a2200937 a 4500 001 1906799 005 2017-09-28 008 2011 bl uuuu u00u1 u #d 024 7 $a10.1371/journal.pone.0018551$2DOI 100 1 $aRUIZ, J. C. 245 $aEvidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains.$h[electronic resource] 260 $c2011 520 $aBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829. 650 $aCaseous lymphadenitis 650 $aGenome 650 $aPathogenicity 650 $aCorynebacterium Pseudotuberculosis 650 $aGenética 650 $aPatógeno 653 $aAnálise de genoma 653 $aGenoma de C pseudotuberculosis 653 $aIlhas de patogenicidade 700 1 $aD'AFONSECA, V. 700 1 $aSILVA, A. 700 1 $aALI, A. 700 1 $aPINTO, A. C. 700 1 $aSANTOS, A. R. 700 1 $aROCHA, A. A. M. C. 700 1 $aLOPES, D. O. 700 1 $aDORELLA, F. A. 700 1 $aPACHECO, L. G. C. 700 1 $aCOSTA, M. P. 700 1 $aTURK, M. Z. 700 1 $aSEYFFERT, N. 700 1 $aMORAES, P. M. R. O. 700 1 $aSOARES, S. C. 700 1 $aALMEIDA, S. S. 700 1 $aCASTRO, T. L. P. 700 1 $aABREU, V. A. C. 700 1 $aTROST, E. 700 1 $aBAUMBACH, J. 700 1 $aTAUCH, A. 700 1 $aSCHNEIDER, M. P. C. 700 1 $aMcCULLOCH, J. 700 1 $aCERDEIRA, L. T. 700 1 $aRAMOS, R. T. J. 700 1 $aZERLOTINI, A. 700 1 $aDOMINITINI, A. 700 1 $aRESENDE, D. M. 700 1 $aCOSER, E. M. 700 1 $aOLIVEIRA, L. M. 700 1 $aPEDROSA, A. L. 700 1 $aVIEIRA, C. U. 700 1 $aGUIMARAES, C. T. 700 1 $aBARTHOLOMEU, D. C. 700 1 $aOLIVEIRA, D. M. 700 1 $aSANTOS, F. R. 700 1 $aRABELO, E. M. 700 1 $aLOBO, F. P. 700 1 $aFRANCO, G. R. 700 1 $aCOSTA, A. F. 700 1 $aCASTRO, I. M. 700 1 $aDIAS, S. R. C. 700 1 $aFERRO, J. A. 700 1 $aORTEGA, J. M. 700 1 $aPAIVA, L. V. 700 1 $aALMEIDA, J. F. 700 1 $aGOULART, L. R. 700 1 $aFERRO, M. I. T. 700 1 $aCARNEIRO, N. P. 700 1 $aFALCÃO, P. R. K. 700 1 $aGRYNBERG, P. 700 1 $aTEIXEIRA, S. M. R. 700 1 $aBROMMONSCHENKEL, S. 700 1 $aOLIVEIRA, S. C. 700 1 $aMEYER, R. 700 1 $aMOORE, R. J. 700 1 $aMIYOSHI, A. 700 1 $aOLIVEIRA, G. C. 700 1 $aAZEVEDO, V. 773 $tPlos One, San Francisco$gv. 6, n. 4, p. 1-16, 2011.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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Registro Completo
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
14/02/2008 |
Data da última atualização: |
16/10/2017 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
SILVA, J. C. da; BETTIOL, W. |
Afiliação: |
JULIANO CESAR DA SILVA, FCA-UNESP; WAGNER BETTIOL, CNPMA. |
Título: |
Possibilidade de controle da murcha de Fusarium do tomateiro com isolados de Fusarium oxysporum não patogênico. |
Ano de publicação: |
2006 |
Fonte/Imprenta: |
Jaguariúna: Embrapa Meio Ambiente, 2006. |
Páginas: |
4 p. |
Série: |
(Embrapa Meio Ambiente. Comunicado Técnico, 36). |
Idioma: |
Português |
Conteúdo: |
O trabalho teve por objetivo verificar o efeito dos isolados de Fusarium oxysporum não patogênicos (143/1, 233, 233/1, 245, 245/1, 251, 251/2 e 257) no controle da murcha de Fusarium causada por Fusarium oxysporum f. sp. lycopersici, raça 2 (isolados C-21A, TO11 e TO245) em plântulas de tomateiro cv. Viradoro. O sistema radicular de plântulas de tomateiro, com 30 dias de idade, foi imerso na suspensão de inóculo dos isolados de F. oxysporum não patogênicos na concentração de 106 conídios mL-1 e em seguida as mudas foram transplantadas para substrato de cultivo. |
Thesagro: |
Controle Biológico; Murcha de Fusarium; Tomate. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/CNPMA/7464/1/comunicado_36.pdf
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Marc: |
LEADER 01169nam a2200181 a 4500 001 1015523 005 2017-10-16 008 2006 bl uuuu u0uu1 u #d 100 1 $aSILVA, J. C. da 245 $aPossibilidade de controle da murcha de Fusarium do tomateiro com isolados de Fusarium oxysporum não patogênico.$h[electronic resource] 260 $aJaguariúna: Embrapa Meio Ambiente$c2006 300 $a4 p. 490 $a(Embrapa Meio Ambiente. Comunicado Técnico, 36). 520 $aO trabalho teve por objetivo verificar o efeito dos isolados de Fusarium oxysporum não patogênicos (143/1, 233, 233/1, 245, 245/1, 251, 251/2 e 257) no controle da murcha de Fusarium causada por Fusarium oxysporum f. sp. lycopersici, raça 2 (isolados C-21A, TO11 e TO245) em plântulas de tomateiro cv. Viradoro. O sistema radicular de plântulas de tomateiro, com 30 dias de idade, foi imerso na suspensão de inóculo dos isolados de F. oxysporum não patogênicos na concentração de 106 conídios mL-1 e em seguida as mudas foram transplantadas para substrato de cultivo. 650 $aControle Biológico 650 $aMurcha de Fusarium 650 $aTomate 700 1 $aBETTIOL, W.
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