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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
05/01/2024 |
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Autoria: |
BAIRD, D. T.; MCNEILLY, A. S. |
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Título: |
Gonadotrophic control of follicular development and function during the oestrous cycle of the ewe. |
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Ano de publicação: |
1981 |
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Fonte/Imprenta: |
Journal Reproduction and Fertility. Supplement, v. 30, p. 119-133, 1981. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: In the adult non-pregnant ewe the secretion of FSH is sufficient to ensure a continuous growth and development of antral follicles to 3-5 mm size at all times. Further development and increased secretion of oestradiol through the final 72 h to ovulation depends on adequate stimulation by LH. During anoestrus and the luteal phase of the cycle LH pulses occur too infrequently to stimulate sufficient oestradiol to evoke an LH surge. Moreover, during the luteal phase progesterone secreted by the corpus luteum not only reduces the frequency of LH pulses but also inhibits the ability of oestrogen to evoke an LH surge. At the time of luteal regression the frequency of LH pulses increases to at least one per hour due to the fall in progesterone secretion. This change in pulse frequency of LH is associated with a decrease in the secretion of FSH, probably because of a direct inhibitory action of oestrogen on the anterior pituitary gland. The dominant follicle is probably relatively independent of circulating levels of FSH due to the high concentration of oestradiol and FSH within the microenvironment of the follicular cavity. Once the oestrogen secretion achieves a certain level a preovulatory surge of LH (and FSH) occurs. Increased sensitivity of the anterior pituitary to LH-RH and increased secretion of LH-RH from the hypothalamus both play a part in producing the LH surge. The rise in prolactin at this time probably reflects a decrease in hypothalamic dopamine turnover which is necessary for maximum release of LH-RH. The preovulatory LH surge initially stimulates and then totally inhibits further secretion of oestrogen and androgen from the ovulatory follicle. This suppression of steroid secretion is accompanied by a second peak of FSH at about the time of ovulation. The function of this second peak of FSH remains unknown although it may be responsible for the development of the large antral follicles which occur on Days 3 and 4. It is probably more important in those mammals like the rat and hamster which only form a functional corpus luteum if pregnancy occurs and in which oestrogen is necessary for implantation. MenosAbstract: In the adult non-pregnant ewe the secretion of FSH is sufficient to ensure a continuous growth and development of antral follicles to 3-5 mm size at all times. Further development and increased secretion of oestradiol through the final 72 h to ovulation depends on adequate stimulation by LH. During anoestrus and the luteal phase of the cycle LH pulses occur too infrequently to stimulate sufficient oestradiol to evoke an LH surge. Moreover, during the luteal phase progesterone secreted by the corpus luteum not only reduces the frequency of LH pulses but also inhibits the ability of oestrogen to evoke an LH surge. At the time of luteal regression the frequency of LH pulses increases to at least one per hour due to the fall in progesterone secretion. This change in pulse frequency of LH is associated with a decrease in the secretion of FSH, probably because of a direct inhibitory action of oestrogen on the anterior pituitary gland. The dominant follicle is probably relatively independent of circulating levels of FSH due to the high concentration of oestradiol and FSH within the microenvironment of the follicular cavity. Once the oestrogen secretion achieves a certain level a preovulatory surge of LH (and FSH) occurs. Increased sensitivity of the anterior pituitary to LH-RH and increased secretion of LH-RH from the hypothalamus both play a part in producing the LH surge. The rise in prolactin at this time probably reflects a decrease in hypothalamic dopamine turnover w... Mostrar Tudo |
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Thesagro: |
Ciclo Estral; Endocrinologia; Estradiol; Ovino; Reprodução. |
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Thesaurus Nal: |
Corpus luteum; Corpus luteum hormones; Endocrine system physiology; Luteinizing hormone; Ovarian follicles; Ovulation; Pituitary gland; Pituitary gonadotropins; Pregnancy; Progesterone; Prolactin; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03102naa a2200337 a 4500
001 1520133
005 2024-01-05
008 1981 bl uuuu u00u1 u #d
100 1 $aBAIRD, D. T.
245 $aGonadotrophic control of follicular development and function during the oestrous cycle of the ewe.
260 $c1981
520 $aAbstract: In the adult non-pregnant ewe the secretion of FSH is sufficient to ensure a continuous growth and development of antral follicles to 3-5 mm size at all times. Further development and increased secretion of oestradiol through the final 72 h to ovulation depends on adequate stimulation by LH. During anoestrus and the luteal phase of the cycle LH pulses occur too infrequently to stimulate sufficient oestradiol to evoke an LH surge. Moreover, during the luteal phase progesterone secreted by the corpus luteum not only reduces the frequency of LH pulses but also inhibits the ability of oestrogen to evoke an LH surge. At the time of luteal regression the frequency of LH pulses increases to at least one per hour due to the fall in progesterone secretion. This change in pulse frequency of LH is associated with a decrease in the secretion of FSH, probably because of a direct inhibitory action of oestrogen on the anterior pituitary gland. The dominant follicle is probably relatively independent of circulating levels of FSH due to the high concentration of oestradiol and FSH within the microenvironment of the follicular cavity. Once the oestrogen secretion achieves a certain level a preovulatory surge of LH (and FSH) occurs. Increased sensitivity of the anterior pituitary to LH-RH and increased secretion of LH-RH from the hypothalamus both play a part in producing the LH surge. The rise in prolactin at this time probably reflects a decrease in hypothalamic dopamine turnover which is necessary for maximum release of LH-RH. The preovulatory LH surge initially stimulates and then totally inhibits further secretion of oestrogen and androgen from the ovulatory follicle. This suppression of steroid secretion is accompanied by a second peak of FSH at about the time of ovulation. The function of this second peak of FSH remains unknown although it may be responsible for the development of the large antral follicles which occur on Days 3 and 4. It is probably more important in those mammals like the rat and hamster which only form a functional corpus luteum if pregnancy occurs and in which oestrogen is necessary for implantation.
650 $aCorpus luteum
650 $aCorpus luteum hormones
650 $aEndocrine system physiology
650 $aLuteinizing hormone
650 $aOvarian follicles
650 $aOvulation
650 $aPituitary gland
650 $aPituitary gonadotropins
650 $aPregnancy
650 $aProgesterone
650 $aProlactin
650 $aSheep
650 $aCiclo Estral
650 $aEndocrinologia
650 $aEstradiol
650 $aOvino
650 $aReprodução
700 1 $aMCNEILLY, A. S.
773 $tJournal Reproduction and Fertility. Supplement$gv. 30, p. 119-133, 1981.
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Embrapa Caprinos e Ovinos (CNPC) |
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