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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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Data corrente: |
04/04/2013 |
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Data da última atualização: |
14/12/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
AZEVEDO, M. M. B.; CHAVES, F. C. M.; ALMEIDA, C. A.; BIZZO, H. R.; DUARTE, R. S.; CAMPOS-TAKAKI, G. M.; ALVIANO, C. S.; ALVIANO, D. S. |
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Afiliação: |
Mariana M. B. Azevedo, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; Catia A. Almeida, IMPG-UFRJ; HUMBERTO RIBEIRO BIZZO, CTAA; Rafael S. Duarte, IMPG-UFRJ; Galba M. Campos-Takaki, Catholic University of Pernambuco; Celuta S. Alviano, IMPG-UFRJ; Daniela S. Alviano, IMPG-UFRJ. |
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Título: |
Antioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
Molecules, v. 18, n. 1, p. 1128-1137, jan. 2013. |
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ISSN: |
1420-3049 |
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DOI: |
10.3390/molecules18011128 |
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Idioma: |
Inglês |
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Conteúdo: |
Croton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice. MenosCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal in... Mostrar Tudo |
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Palavras-Chave: |
Atividade antimicrobiana; Atividade antioxidante; Óleos essenciais; Sacaca. |
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Thesagro: |
Óleo Essencial. |
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Thesaurus Nal: |
Croton cajucara. |
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Categoria do assunto: |
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X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/80491/1/molecules-18-01128.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/88878/1/2013-060.pdf
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Marc: |
LEADER 02431naa a2200301 a 4500
001 1955000
005 2017-12-14
008 2013 bl uuuu u00u1 u #d
022 $a1420-3049
024 7 $a10.3390/molecules18011128$2DOI
100 1 $aAZEVEDO, M. M. B.
245 $aAntioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth.
260 $c2013
520 $aCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice.
650 $aCroton cajucara
650 $aÓleo Essencial
653 $aAtividade antimicrobiana
653 $aAtividade antioxidante
653 $aÓleos essenciais
653 $aSacaca
700 1 $aCHAVES, F. C. M.
700 1 $aALMEIDA, C. A.
700 1 $aBIZZO, H. R.
700 1 $aDUARTE, R. S.
700 1 $aCAMPOS-TAKAKI, G. M.
700 1 $aALVIANO, C. S.
700 1 $aALVIANO, D. S.
773 $tMolecules$gv. 18, n. 1, p. 1128-1137, jan. 2013.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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| Registros recuperados : 31 | |
| 21. |  | AZEVEDO, M. M. B. de; CHAVES, F. C. M.; BLANK, A. F.; BIZZO, H. R.; ALVIANO, D. S.; ALVIANO, C. S. Bioactivity assessment of essential oils from piper and croton in Cryptococcus neoformans. In: CONGRESSO BRASILEIRO DE MICOLOGIA, 8., 2016, Florianópolis. Anais... São Paulo: Sociedade Brasileira de Micologia, 2016. p. 845.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 22. | | AZEVEDO, M. M. B.; ALMEIDA, C. A.; CHAVES, F. C. M.; RICCI-JÚNIOR, E.; GARCIA, A. R.; RODRIGUES, I. A.; ALVIANO, C. S.; ALVIANO, D. S. Croton cajucara essential oil nanoemulsion and its antifungal activities. Processes, v. 9, art. 1872, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
|  |
| 23. | | RODRIGUES, I. A.; AZEVEDO, M. M. B.; ALMEIDA, C. A.; CHAVES, F. C. M.; ALVIANO, D. S.; ALVIANO, C. S.; ROSA, M. S. S.; VERMELHO, A. B. Efeito citocida dos extratos de Arrabidaea chica em Leishmania spp. e Trypanosoma cruzi. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 26., 2011, Foz do Iguaçu. Resumos. Foz do Iguaçu: Sociedade Brasileira de Microbiologia, 2011.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
| |
| 24. | | AZEVEDO, M. M. B.; ALMEIDA, C. A.; CHAVES, F. C. M.; CAMPOS-TAKAKI, G. M.; ROZENTAL, S.; BIZZO, H. R.; ALVIANO, C. S.; ALVIANO, D. S. Effects of 7-Hydroxycalamenene isolated from Croton cajucara essential oil on growth, lipid content and ultrastructural aspects of Rhizopus oryzae. Planta Medica, v. 80, p. 550-556, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| 26. | | AZEVEDO, M. M. B. de; ALMEIDA, C. A.; FREITAS, F. C.; BERGTER, E. B.; BIZZO, H. R.; ALVIANO, C. S.; ALVIANO, D. S. In vitro evaluation of inhibitory activity of some species of croton and piper essential oils in secreted proteases of Pseudallescheria boydii. In: BRAZILIAN SYMPOSIUM ON ESSENTIAL OILS, 8. - INTERNATIONAL SYMPOSIUM ON ESSENTIAL OILS. Rio de Janeiro, 2015. Proceedings... [Campinas]: Infobiblos, 2015. 1 p. Poster 080. SBOE 2015.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 27. | | AZEVEDO, M. M. B. de; ALMEIDA, C. A.; SILVA, M. B. F. C. da; CHAVES, F. C. M.; RICCI JÚNIOR, E.; BIZZO, H. R.; ALVIANO, D. S.; ALVIANO, C. S. Antifungal activity of 7-hydroxycalamenene-rich essential oil nanoemulsion. In: CONGRESSO BRASILEIRO DE MICOLOGIA, 8., Florianópolis. Anais… s.l.: Sociedade Brasileira de Micologia, 2016. p. 846.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| 28. | | AZEVEDO, M. M. B. de; ALMEIDA, C. A.; CHAVES, F. C. M.; GAMA, P. E.; CUNHA, A. L. B. da; BATISTA, A. C.; SANTOS, E. da S.; BIZZO, H. R.; ALVIANO, C. S. Inibição da atividade proteásica de Candida albicans pelos óleos essenciais de quatro espécies de Piper. Trabalho apresentado no VII SBOE - Simpósio Brasileiro de Óleos Essenciais, Santarém, 2013.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| 29. | | AZEVEDO, M. M. B. de; ALMEIDA, C. A.; CHAVES, F. C. M.; GAMA, P. E.; CUNHA, A. L. B. da; BATISTA, A. C.; SANTOS, E. da S.; BIZZO, H. R.; ALVIANO, C. S. Inibição do crescimento de Rhizopus oryzae pelos óleos essenciais de Piper hispidum, Piper marginatum, Piper tuberculatum e Piper sp.: efeito no biofilme e na atividade peptidásica. Trabalho apresentado no VII SBOE - Simpósio Brasileiro de Óleos Essenciais, Santarém, 2013.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| 30. | | ALMEIDA, C. A.; AZEVEDO, M. M. B.; CHAVES, F. C. M.; OLIVEIRA, M. R. de; RODRIGUES, I. A.; BIZZO, H. R.; GAMA, P. E.; ALVIANO, D. S.; ALVIANO, C. S. Piper essential oils inhibit Rhizopus oryzae growth, biofilm formation, and Rhizopuspepsin activity. Canadian Journal of Infectious Diseases and Medical Microbiology, 2018.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| 31. | | RODRIGUES, I. A.; AZEVEDO, M. M. B.; CHAVES, F. C. M.; BIZZO, H. R.; CORTE-REAL, S.; ALVIANO, D. S.; ALVIANO, C. S.; ROSA, M. S. S.; VERMELHO, A. B. In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi. BMC Complementary and Alternative Medicine, v. 13, n. 1, p. 249, Oct. 2013.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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| Registros recuperados : 31 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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