|
Registro Completo |
|
Biblioteca(s): |
Embrapa Amazônia Ocidental. |
|
Data corrente: |
29/12/2022 |
|
Data da última atualização: |
01/06/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
GARCIA, A. R.; AMARAL, A. C. F.; MARIA, A. C. B.; PAZ, M. M.; AMORIM, M. M. B.; CHAVES, F. C. M.; VERMELHO, A. B.; NICO, D.; RODRIGUES, I. A. |
|
Afiliação: |
ANDREZA R. GARCIA, Universidade Federal do Rio de Janeiro; ANA CLAUDIA F. AMARAL, FIOCRUZ; ANA CLARA B. MARIA, FIOCRUZ; MARIANA M. PAZ, Universidade Federal do Rio de Janeiro; MARIANA M. B. AMORIM, Instituto Municipal de Vigilância Sanitária, Rio de Janeiro; FRANCISCO CELIO MAIA CHAVES, CPAA; ALANE B. VERMELHO, Universidade Federal do Rio de Janeiro; DIRLEI NICO, Universidade Federal do Rio de Janeiro; IGOR A. RODRIGUES, Universidade Federal do Rio de Janeiro. |
|
Título: |
Antileishmanial screening, cytotoxicity, and chemical composition of essential oils: a special focus on Piper callosumessential oil. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Chemistry and Biodiversity, v. 20, e202200689, 2023. |
|
DOI: |
https://doi.org/10.1002/cbdv.202200689 |
|
Idioma: |
Inglês |
|
Conteúdo: |
In the present study, we screened a panel of fourteen EO for their chemical composition and in vitro antileishmanial activity agaisnt L. amazonensis, the etiological agent of tegumentary leishmaniasis. Cytotoxicity was also evaluated against different mammalian cells to provide initial evidence of their safety. In addition, the mode of action of Piper callosum(the most effective EO) was investigated. |
|
Palavras-Chave: |
Antileishmanial activity; Drug screening; Drug selectivity; Tegumentary leishmaniasis; Volatileoils. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 01318naa a2200289 a 4500
001 2150466
005 2023-06-01
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1002/cbdv.202200689$2DOI
100 1 $aGARCIA, A. R.
245 $aAntileishmanial screening, cytotoxicity, and chemical composition of essential oils$ba special focus on Piper callosumessential oil.$h[electronic resource]
260 $c2023
520 $aIn the present study, we screened a panel of fourteen EO for their chemical composition and in vitro antileishmanial activity agaisnt L. amazonensis, the etiological agent of tegumentary leishmaniasis. Cytotoxicity was also evaluated against different mammalian cells to provide initial evidence of their safety. In addition, the mode of action of Piper callosum(the most effective EO) was investigated.
653 $aAntileishmanial activity
653 $aDrug screening
653 $aDrug selectivity
653 $aTegumentary leishmaniasis
653 $aVolatileoils
700 1 $aAMARAL, A. C. F.
700 1 $aMARIA, A. C. B.
700 1 $aPAZ, M. M.
700 1 $aAMORIM, M. M. B.
700 1 $aCHAVES, F. C. M.
700 1 $aVERMELHO, A. B.
700 1 $aNICO, D.
700 1 $aRODRIGUES, I. A.
773 $tChemistry and Biodiversity$gv. 20, e202200689, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
|
