Data/hora: 03/06/2024 02:41:49

Biblioteca(s): 	Embrapa Gado de Leite.	
Data corrente: 	06/01/2020	
Data da última atualização: 	06/02/2024	
Autoria: 	ZANETTE, R. S. S.; ALMEIDA, L. B. F. DE; SOUZA, N. L. G. D.; ALMEIDA, C. G. DE; OLIVEIRA, L. F. C. DE; MATOS, ELYABE M. DE; GERN, J. C.; BRANDAO, H. de M.; MUNK, M.	
Afiliação: 	Rafaella S. S. Zanette; Leonara B. F. de Almeida; Nelson L. G. D. Souza; Camila G. de Almeida; Luiz F. C. de Oliveira; Elyabe M. de Matos; JULIANA CARINE GERN, CNPGL; HUMBERTO DE MELLO BRANDAO, CNPGL; Michele Munk.	
Título: 	Cotton cellulose nanofiber/chitosan nanocomposite: characterization and evaluation of cytocompatibility.	
Ano de publicação: 	2019	
Fonte/Imprenta: 	Journal of Biomaterials Science, Polymer Edition, v. 30, n. 16, p. 1489-1504, 2019.	
DOI: 	https://doi.org/10.1080/09205063.2019.1646627	
Idioma: 	Inglês	
Conteúdo: 	Cellulose is a renewable polymer quite abundant on the Earth and very attractive for applications in the construction of eco-friendly biomedical products. The aim of this study was to investigate the chemical-physical characteristics of cotton cellulose nanofiber (CCN)/chitosan nanocomposite and its cytocompatibility with human embryonic kidney cells. First, the chemical composition, swelling ratio and surface topography of the nanocomposite were evaluated. Cytocompatibility was then assessed through spreading, proliferation and viability of cells. The experimental results showed that the CCN was an effective nanomaterial agent for increasing the roughness surface of chitosan film. Cell proliferation and changes in cell morphology indicated that the nanocomposite led to improved cell spreading and growth. Cell viability did not decrease after 24&#8201;h. However, the cell survival on the nanocomposite was affected at 72&#8201;h. The results indicate that CCN/chitosan nanocomposite could be a promising biocompatible biomaterial for biomedical applications.	
Palavras-Chave: 	Biomaterials; Biopolymer; In vitro cell culture; Nanotopography; Polymeric nanomaterials.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Gado de Leite (CNPGL)	
Exemplares: 	CNPGL - (24938-1) - UPC - AP - DD -  -  -  - DIS