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Registro Completo |
Biblioteca(s): |
Embrapa Agroenergia. |
Data corrente: |
23/11/2022 |
Data da última atualização: |
23/11/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CARNEIRO, C. V. G. C.; SERRA, L. A.; PACHECO, T. F.; FERREIRA, L. M. M.; DUARTE, L. T.; FREITAS, M. N. de M.; TRICHEZ, D.; ALMEIDA, J. R. M. de. |
Afiliação: |
CLARA VIDA GALRÃO CORRÊA CARNEIRO, UNB/CNPAE; LUANA ASSIS SERRA, UNB/CNPAE; THALYTA FRAGA PACHECO, CNPAE; LETÍCIA MARIA MALLMANN FERREIRA, UNB/CNPAE; LIVIA TEIXEIRA DUARTE BRANDAO, CNPAE; MARIANA NOGUEIRA DE MOURA FREITAS, UNB/CNPAE; DÉBORA TRICHEZ, UNB/CNPAE; JOAO RICARDO MOREIRA DE ALMEIDA, CNPAE. |
Título: |
Advances in Komagataella phaffii Engineering for the Production of Renewable Chemicals and Proteins |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Fermentation, v. 8, n. 575, p. 2-37, 2022. |
DOI: |
https://doi.org/10.3390/fermentation8110575 |
Idioma: |
Inglês |
Conteúdo: |
The need for a more sustainable society has prompted the development of bio-based processes to produce fuels, chemicals, and materials in substitution for fossil-based ones. In this context, microorganisms have been employed to convert renewable carbon sources into various products. The methylotrophic yeast Komagataella phaffii has been extensively used in the production of heterologous proteins. More recently, it has been explored as a host organism to produce various chemicals through new metabolic engineering and synthetic biology tools. This review first summarizes Komagataella taxonomy and diversity and then highlights the recent approaches in cell engineering to produce renewable chemicals and proteins. Finally, strategies to optimize and develop new fermentative processes using K. phaffii as a cell factory are presented and discussed. The yeast K. phaffii shows an outstanding performance for renewable chemicals and protein production due to its ability to metabolize different carbon sources and the availability of engineering tools. Indeed, it has been employed in producing alcohols, carboxylic acids, proteins, and other compounds using different carbon sources, including glycerol, glucose, xylose, methanol, and even CO2. |
Palavras-Chave: |
Komagataella phaffii. |
Thesagro: |
Biologia Vegetal. |
Thesaurus Nal: |
Bioengineering; Pichia pastoris. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1148607/1/Advances-in-komagataella-phaffii.pdf
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Marc: |
LEADER 02069naa a2200265 a 4500 001 2148607 005 2022-11-23 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/fermentation8110575$2DOI 100 1 $aCARNEIRO, C. V. G. C. 245 $aAdvances in Komagataella phaffii Engineering for the Production of Renewable Chemicals and Proteins$h[electronic resource] 260 $c2022 520 $aThe need for a more sustainable society has prompted the development of bio-based processes to produce fuels, chemicals, and materials in substitution for fossil-based ones. In this context, microorganisms have been employed to convert renewable carbon sources into various products. The methylotrophic yeast Komagataella phaffii has been extensively used in the production of heterologous proteins. More recently, it has been explored as a host organism to produce various chemicals through new metabolic engineering and synthetic biology tools. This review first summarizes Komagataella taxonomy and diversity and then highlights the recent approaches in cell engineering to produce renewable chemicals and proteins. Finally, strategies to optimize and develop new fermentative processes using K. phaffii as a cell factory are presented and discussed. The yeast K. phaffii shows an outstanding performance for renewable chemicals and protein production due to its ability to metabolize different carbon sources and the availability of engineering tools. Indeed, it has been employed in producing alcohols, carboxylic acids, proteins, and other compounds using different carbon sources, including glycerol, glucose, xylose, methanol, and even CO2. 650 $aBioengineering 650 $aPichia pastoris 650 $aBiologia Vegetal 653 $aKomagataella phaffii 700 1 $aSERRA, L. A. 700 1 $aPACHECO, T. F. 700 1 $aFERREIRA, L. M. M. 700 1 $aDUARTE, L. T. 700 1 $aFREITAS, M. N. de M. 700 1 $aTRICHEZ, D. 700 1 $aALMEIDA, J. R. M. de 773 $tFermentation$gv. 8, n. 575, p. 2-37, 2022.
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Embrapa Agroenergia (CNPAE) |
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Registro Completo
Biblioteca(s): |
Embrapa Hortaliças. |
Data corrente: |
19/10/1998 |
Data da última atualização: |
19/10/1998 |
Autoria: |
OLIVEIRA, A. T. de; JUNQUEIRA, A. M. R.; PEIXOTO; J. R.; FRANCA, F. H. |
Afiliação: |
EMBRAPA-CNPH, Brasilia, DF. |
Título: |
Impacto da irrigacao por aspersao convencional nos danos da traca-das-cruciferas (Plutella xylostella) em plantas de repolho. |
Ano de publicação: |
1998 |
Fonte/Imprenta: |
In: CONGRESSO DE INICIACAO CIENTIFICA DA UnB, 4., 1998, Brasilia, DF. Anais... Brasilia: UnB, 1998. |
Páginas: |
p.20. |
Idioma: |
Português |
Palavras-Chave: |
Brasil; Brasilia; Brasssica oleracea capitata; Cabbages; Damage; Distrito Federal; Pest insect; Plant diseases. |
Thesagro: |
Aspersão; Brassica Oleracea Capitata; Cerrado; Dano; Doença de Planta; Inseto; Irrigação; Irrigação por Aspersão; Plutella Xylostella; Praga; Repolho. |
Thesaurus NAL: |
Brazil; cabbage; sprinkler irrigation. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01209naa a2200433 a 4500 001 1761922 005 1998-10-19 008 1998 bl uuuu u00u1 u #d 100 1 $aOLIVEIRA, A. T. de 245 $aImpacto da irrigacao por aspersao convencional nos danos da traca-das-cruciferas (Plutella xylostella) em plantas de repolho. 260 $c1998 300 $ap.20. 650 $aBrazil 650 $acabbage 650 $asprinkler irrigation 650 $aAspersão 650 $aBrassica Oleracea Capitata 650 $aCerrado 650 $aDano 650 $aDoença de Planta 650 $aInseto 650 $aIrrigação 650 $aIrrigação por Aspersão 650 $aPlutella Xylostella 650 $aPraga 650 $aRepolho 653 $aBrasil 653 $aBrasilia 653 $aBrasssica oleracea capitata 653 $aCabbages 653 $aDamage 653 $aDistrito Federal 653 $aPest insect 653 $aPlant diseases 700 1 $aJUNQUEIRA, A. M. R. 700 1 $aPEIXOTO 700 1 $aJ. R. 700 1 $aFRANCA, F. H. 773 $tIn: CONGRESSO DE INICIACAO CIENTIFICA DA UnB, 4., 1998, Brasilia, DF. Anais... Brasilia: UnB, 1998.
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