| |
|
|
| Registros recuperados : 650 | |
| 177. |  | ABREU, U. G. P. de; CARVALHO, T. B. de; MORAES, A. S. Preço do bezerro pago no Pantanal da Nhecolândia - MS, no período de 2001 a 2008. REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 46., 2009, Maringá, PR. Inovação científica e tecnológica em zootecnia: anais. Maringá, PR: SBZ, 2009. Disponível também no CD2009.00004.| Biblioteca(s): Embrapa Pantanal. |
|   |
| Registros recuperados : 650 | |
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
|
Data corrente: |
21/11/2018 |
|
Data da última atualização: |
29/11/2019 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 1 |
|
Autoria: |
OLIVEIRA, P. S. N. de; COUTINHO, L. L.; TIZIOTO, P. C.; CESAR, A. S. M.; OLIVEIRA, G. B. de; DINIZ, W, J. da S.; LIMA, A. O. de; REECY, J. M.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REGITANO, L. C. de A. |
|
Afiliação: |
Priscila Silva Neubern de Oliveira, Bolsista/Embrapa Pecuária Sudeste; Luiz L. Coutinho, USP; Polyana C. Tizioto, NGS Genomic Solutions; Aline S. M. Cesar, USP; Gabriella B. de Oliveira, USP; Wellison J. da S. Diniz, UFSCAR; Andressa O. de Lima, UFSCAR; James M. Reecy, Iowa State University; Gerson B. Mourão, USP; ADHEMAR ZERLOTINI NETO, CNPTIA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
|
Título: |
An integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle. |
|
Ano de publicação: |
2019 |
|
Fonte/Imprenta: |
Scientific Reports, v. 8, n. 17072, 2018. |
|
DOI: |
10.1038/s41598-018-35315-5 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Residual Feed Intake (RFI) is an economically relevant trait in beef cattle. Among the molecular regulatory mechanisms, microRNAs (miRNAs) are an important dimension in post-transcriptional regulation and have been associated with different biological pathways. Here, we performed differential miRNAs expression and weighted gene co-expression network analyses (WGCNA) to better understand the complex interactions between miRNAs and mRNAs expressed in bovine skeletal muscle and liver. MiRNA and mRNA expression data were obtained from Nelore steers that were genetically divergent for RFI (N = 10 [low RFI or feed efficient]; N = 10 [high RFI or feed inefficient]). Differentially expressed and hub miRNAs such as bta-miR-486, bta-miR-7, bta-miR15a, bta-miR-21, bta-miR 29, btamiR- 30b, bta-miR-106b, bta-miR-199a-3p, bta-miR-204, and bta-miR 296 may have a potential role in variation of RFI. Functional enrichment analysis of differentially expressed (DE) miRNA?s target genes and miRNA?mRNA correlated modules revealed that insulin, lipid, immune system, oxidative stress and muscle development signaling pathways might potentially be involved in RFI in this population. Our study identified DE miRNAs, miRNA - mRNA regulatory networks and hub miRNAs related to RFI. These findings suggest a possible role of miRNAs in regulation of RFI, providing new insights into the potential molecular mechanisms that control feed efficiency in Nelore cattle. |
|
Palavras-Chave: |
MiRNA; RFI. |
|
Thesagro: |
Gado Nelore. |
|
Thesaurus NAL: |
Beef cattle; Nellore; Skeletal muscle. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/186529/1/An-integrative-transcriptome.pdf
|
|
Marc: |
LEADER 02400naa a2200325 a 4500
001 2099755
005 2019-11-29
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1038/s41598-018-35315-5$2DOI
100 1 $aOLIVEIRA, P. S. N. de
245 $aAn integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle.$h[electronic resource]
260 $c2019
520 $aResidual Feed Intake (RFI) is an economically relevant trait in beef cattle. Among the molecular regulatory mechanisms, microRNAs (miRNAs) are an important dimension in post-transcriptional regulation and have been associated with different biological pathways. Here, we performed differential miRNAs expression and weighted gene co-expression network analyses (WGCNA) to better understand the complex interactions between miRNAs and mRNAs expressed in bovine skeletal muscle and liver. MiRNA and mRNA expression data were obtained from Nelore steers that were genetically divergent for RFI (N = 10 [low RFI or feed efficient]; N = 10 [high RFI or feed inefficient]). Differentially expressed and hub miRNAs such as bta-miR-486, bta-miR-7, bta-miR15a, bta-miR-21, bta-miR 29, btamiR- 30b, bta-miR-106b, bta-miR-199a-3p, bta-miR-204, and bta-miR 296 may have a potential role in variation of RFI. Functional enrichment analysis of differentially expressed (DE) miRNA?s target genes and miRNA?mRNA correlated modules revealed that insulin, lipid, immune system, oxidative stress and muscle development signaling pathways might potentially be involved in RFI in this population. Our study identified DE miRNAs, miRNA - mRNA regulatory networks and hub miRNAs related to RFI. These findings suggest a possible role of miRNAs in regulation of RFI, providing new insights into the potential molecular mechanisms that control feed efficiency in Nelore cattle.
650 $aBeef cattle
650 $aNellore
650 $aSkeletal muscle
650 $aGado Nelore
653 $aMiRNA
653 $aRFI
700 1 $aCOUTINHO, L. L.
700 1 $aTIZIOTO, P. C.
700 1 $aCESAR, A. S. M.
700 1 $aOLIVEIRA, G. B. de
700 1 $aDINIZ, W, J. da S.
700 1 $aLIMA, A. O. de
700 1 $aREECY, J. M.
700 1 $aMOURÃO, G. B.
700 1 $aZERLOTINI NETO, A.
700 1 $aREGITANO, L. C. de A.
773 $tScientific Reports$gv. 8, n. 17072, 2018.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
